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NCT02847481 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate Fecal Microbiota Transplantation Engraftment in IBS
A Phase 1 study, sponsored by Beth Israel Deaconess Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 80
- Enrollment target
NCT02847481: Completed Phase 1 study, sponsored by Beth Israel Deaconess Medical Center.
NCT02847481 is a Phase 1 study that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 80 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02847481, a Phase 1 study, has completed, sponsored by Beth Israel Deaconess Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 80 participants
- Enrollment target
Study Summary
This is a randomized pilot study to characterize engraftment of a donor's microflora onto patients with Irritable Bowel Syndrome with diarrhea following fecal microbiota transplantation.
Primary Outcome
Stable engraftment will be defined with the Jensen-Shannon Divergence (JSD) between the bacteria community measured in the donor and recipient. Engraftment scores will be defined by the ratio between the JSD in comparison between the recipient and donor and the recipient and other healthy donors not providing material for their FMT.
Interventions
- PROCEDURE fecal microbiota transplantation
- DRUG placebo fecal microbiota transplantation
- PROCEDURE FMT with antibiotic pre-treatment (v1)
- PROCEDURE FMT with antibiotic pre-treatment (v2)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2016-05 |
| Est. Completion | 2018-08-05 |
| Phase | Phase 1 |
What the finished NCT02847481 record still lists
NCT02847481 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher).
The record links to 0 conditions, and to 4 interventions - of which fecal microbiota transplantation is the first listed.
NCT02847481 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02847481 about?
NCT02847481 is a clinical study titled "A Study to Evaluate Fecal Microbiota Transplantation Engraftment in IBS". This is a randomized pilot study to characterize engraftment of a donor's microflora onto patients with Irritable Bowel Syndrome with diarrhea following fecal microbiota transplantation.
What is the current status of trial NCT02847481?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2016-05. Estimated completion is 2018-08-05.
What interventions are being tested in trial NCT02847481?
The interventions under investigation include: fecal microbiota transplantation (PROCEDURE), placebo fecal microbiota transplantation (DRUG), FMT with antibiotic pre-treatment (v1) (PROCEDURE), FMT with antibiotic pre-treatment (v2) (PROCEDURE).
Who is sponsoring clinical trial NCT02847481?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02847481's enrollment target sits among peer trials
80 672nd of 2000 higher than 1,305 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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