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NCT02836067 · ClinicalTrials.gov registry record · NA
Impact of Smoking and Its Cessation on Systemic and Airway Immune Activation
A NA study, sponsored by Boston Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 53
- Enrollment target
NCT02836067: Completed NA study, sponsored by Boston Medical Center.
NCT02836067 is a NA study that has completed, run by Boston Medical Center. The registered enrollment target is 53 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02836067, a NA study, has completed, sponsored by Boston Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 53 participants
- Enrollment target
Study Summary
The purpose of this study is to learn how smoking affects the immune systems in people with HIV infection. The investigators would like to know if HIV infected smokers who quit smoking have different responses in their tissues from people who keep smoking.
Primary Outcome
Aliquots of BAL and PBMC will be stained for surface antibodies to distinguish differentiation and activation markers. Monocyte cells will be phenotyped by CD3, CD19 and CD56 all on FITC, CD14 BUV 395, CD16 BV510, CCR2 PE, CX3CR1 APC, CD11c PEcf594, CD80 BV 421, CD86 BV 605, HLA-DR BV785, CD123 PE Cy7 and eFluor780 fixable viability dye. T cell populations will be stained for CD3, CD4, CD8, CD45RA, CCR7, CD27 and CD28; activation status by expression of CD25, CD38, CD69, HLA-DR, OX40. We will de
Interventions
- BEHAVIORAL Questionnaires
- PROCEDURE Bronchoscopy
- PROCEDURE Blood Draw
- BEHAVIORAL Counseling
- OTHER Smoking Cessation drugs
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 53 participants |
| Start Date | 2017-06-15 |
| Est. Completion | 2023-12-31 |
| Phase | NA |
What the finished NCT02836067 record still lists
NCT02836067 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 53 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 5 interventions - of which Questionnaires is the first listed.
NCT02836067 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02836067 about?
NCT02836067 is a clinical study titled "Impact of Smoking and Its Cessation on Systemic and Airway Immune Activation". The purpose of this study is to learn how smoking affects the immune systems in people with HIV infection. The investigators would like to know if HIV infected smokers who quit smoking have different responses in their tissues from people who keep smoking.
What is the current status of trial NCT02836067?
This trial is currently completed. It is a NA study. The enrollment target is 53 participants. The study started on 2017-06-15. Estimated completion is 2023-12-31.
What interventions are being tested in trial NCT02836067?
The interventions under investigation include: Questionnaires (BEHAVIORAL), Bronchoscopy (PROCEDURE), Blood Draw (PROCEDURE), Counseling (BEHAVIORAL), Smoking Cessation drugs (OTHER).
Who is sponsoring clinical trial NCT02836067?
This trial is sponsored by Boston Medical Center, which has 253 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02836067's enrollment target sits among peer trials
53 1271st of 2000 higher than 729 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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