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NCT02835846 · ClinicalTrials.gov registry record · Phase 4
Investigation of the Effect of the Female Urinary Microbiome on Incontinence
A Phase 4 study, sponsored by Loyola University.
- Completed
- Registry status
- Phase 4
- Development phase
- 35
- Enrollment target
NCT02835846: Completed Phase 4 study, sponsored by Loyola University.
NCT02835846 is a Phase 4 study that has completed, run by Loyola University. The registered enrollment target is 35 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02835846, a Phase 4 study, has completed, sponsored by Loyola University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 35 participants
- Enrollment target
Study Summary
This purpose of this study is to understand the types of bacteria that are in the bladder and vagina in patients with overactive bladder (OAB) symptoms and understand if the types of bacteria change when with the use of estrogen in the vagina. The investigators are also trying to understand how estrogen influences the body's ability to make substances called peptides that can kill bacteria.
Primary Outcome
The relative abundance of Lactobacillus to total microbes per sample was measured before and after treatment. The within-participant change in relative abundance of Lactobacillus was calculated subtracting pre-treatment from post-treatment.
Interventions
- DRUG Estrogen Cream
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2016-09 |
| Est. Completion | 2018-05 |
| Phase | Phase 4 |
What the finished NCT02835846 record still lists
NCT02835846 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which Estrogen Cream is the first listed.
NCT02835846 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02835846 about?
NCT02835846 is a clinical study titled "Investigation of the Effect of the Female Urinary Microbiome on Incontinence". This purpose of this study is to understand the types of bacteria that are in the bladder and vagina in patients with overactive bladder (OAB) symptoms and understand if the types of bacteria change when with the use of estrogen in the vagina. The investigators are also trying to understand how estr...
What is the current status of trial NCT02835846?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 35 participants. The study started on 2016-09. Estimated completion is 2018-05.
What interventions are being tested in trial NCT02835846?
The interventions under investigation include: Estrogen Cream (DRUG).
Who is sponsoring clinical trial NCT02835846?
This trial is sponsored by Loyola University, which has 92 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02835846's enrollment target sits among peer trials
35 1506th of 2000 higher than 481 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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