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NCT02806310 · ClinicalTrials.gov registry record
Podocan and Wnt Pathway in the Development of Aortopathy in Bicuspid Valve Disease
A clinical trial, sponsored by Bassett Healthcare.
- Completed
- Registry status
- 29
- Enrollment target
NCT02806310: Completed study, sponsored by Bassett Healthcare.
NCT02806310 is a clinical trial that has completed, run by Bassett Healthcare. The registered enrollment target is 29 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02806310 has completed, sponsored by Bassett Healthcare.
- COMPLETED
- Registry status
- 29 participants
- Enrollment target
Study Summary
Bicuspid Aortic Valve (BAV) disease is a common cardiac anomaly that is associated with valvular abnormalities, both stenosis and regurgitation, and aortopathy. It is also shown to play role in abnormal aortic distensibility and stiffness with impairment of aortic elasticity and Left ventricular dysfunction. Mechanism of aortopathy is complex and is not understood completely. In a recent study podocan is found in extracellular matrix (ECM) of human aorta and is found to be accumulated in human abdominal aortic aneurysms. There is no current effective therapy that can alter the progression of aortic dilatation in bicuspid valve disease. Aortic surgery and aortoplasty is the only treatment in severely dilated aorta and aortic dissection. In this study the aim is to investigate the association between podocan and Wnt pathway in development and pathogenesis of aortopathy. This could provide more effective and physiological understanding of disease process and potential target in prevention and treatment for aortopathy.
Interventions
- OTHER Blood draw
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2016-06 |
| Est. Completion | 2020-12 |
What the finished NCT02806310 record still lists
NCT02806310 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 29 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Blood draw is the first listed.
NCT02806310 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02806310 about?
NCT02806310 is a clinical study titled "Podocan and Wnt Pathway in the Development of Aortopathy in Bicuspid Valve Disease". Bicuspid Aortic Valve (BAV) disease is a common cardiac anomaly that is associated with valvular abnormalities, both stenosis and regurgitation, and aortopathy. It is also shown to play role in abnormal aortic distensibility and stiffness with impairment of aortic elasticity and Left ventricular dys...
What is the current status of trial NCT02806310?
This trial is currently completed. The enrollment target is 29 participants. The study started on 2016-06. Estimated completion is 2020-12.
What interventions are being tested in trial NCT02806310?
The interventions under investigation include: Blood draw (OTHER).
Who is sponsoring clinical trial NCT02806310?
This trial is sponsored by Bassett Healthcare, which has 16 total clinical trials registered on ClinicalTrials.gov.
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