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NCT02792998 · ClinicalTrials.gov registry record · Phase 1
A Trial of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Healthy Subjects
A Phase 1 study of Healthy, sponsored by Cyclerion Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 67
- Enrollment target
- 1
- Study location
NCT02792998: Completed Phase 1 study of Healthy, sponsored by Cyclerion Therapeutics.
NCT02792998 is a Phase 1 study of Healthy that has completed, run by Cyclerion Therapeutics. The registered enrollment target is 67 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02792998, a Phase 1 study of Healthy, has completed, sponsored by Cyclerion Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 67 participants
- Enrollment target
- 1
- Study location
Study Summary
The objectives of this study are: Stage 1: To assess the safety, tolerability, pharmacokinetic (PK) profile and pharmacodynamic (PD) effects of a range of doses of IW-1701 tablets administered orally to healthy subjects over 7 days of repeated dosing Stage 2: To assess the safety, tolerability, PK profile and PD effects of IW-1701 tablets administered orally to healthy subjects, in fed and fasted states, in an open-label, single-dose, 2-period, 2-sequence crossover study.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG IW-1701
Study Locations (1)
Texas
- ICON Early Phase Unit - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 67 participants |
| Start Date | 2016-05 |
| Est. Completion | 2016-11 |
| Phase | Phase 1 |
What the finished NCT02792998 record still lists
NCT02792998 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 67 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT02792998 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT02792998 about?
NCT02792998 is a clinical study titled "A Trial of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Healthy Subjects". The objectives of this study are: Stage 1: To assess the safety, tolerability, pharmacokinetic (PK) profile and pharmacodynamic (PD) effects of a range of doses of IW-1701 tablets administered orally to healthy subjects over 7 days of repeated dosing Stage 2: To assess the safety, tolerability, PK...
What is the current status of trial NCT02792998?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 67 participants. The study started on 2016-05. Estimated completion is 2016-11.
What conditions does trial NCT02792998 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT02792998?
The interventions under investigation include: Placebo (DRUG), IW-1701 (DRUG).
Who is sponsoring clinical trial NCT02792998?
This trial is sponsored by Cyclerion Therapeutics, which has 11 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02792998 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02792998's enrollment target sits among peer trials
67 341st of 1090 higher than 750 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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