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NCT02783768 · ClinicalTrials.gov registry record · Early Phase 1
Ventilation and Pulmonary Endothelium Toxicities of E-cigarettes: A Randomized Crossover Pilot Study
A Early Phase 1 study, sponsored by Columbia University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 12
- Enrollment target
NCT02783768 is a Early Phase 1 study that has completed, run by Columbia University. The registered enrollment target is 12 participants.
The verdict
NCT02783768, a Early Phase 1 study, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
Determination of the acute pulmonary toxicities of e-cigarettes in young adults is of major public health importance, as e-cigarette vapor contains established toxicants that as hypothesized cause acute damage to the airways and the pulmonary microvasculature that may promote the development of CLD, for which there remain few effective therapies. The study therefore propose a pilot study using a randomized crossover design in ten healthy young adults to test the acute effects of a standardized e-cigarette exposure on two sensitive, safe, non-invasive imaging measures: (1) ventilation defects on hyperpolarized helium-enhanced magnetic resonance imaging, and (2) pulmonary microvascular blood flow on gadolinium-enhanced pulmonary magnetic resonance angiography.
Interventions
- OTHER Sham
- DRUG Gadolinium
- DEVICE E-cigarette
- DRUG Hyperpolarized 3-Helium
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2017-03-01 |
| Est. Completion | 2018-07-24 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02783768
The ClinicalTrials.gov registry entry for NCT02783768 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Sham is the first listed.
NCT02783768 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02783768 about?
NCT02783768 is a clinical study titled "Ventilation and Pulmonary Endothelium Toxicities of E-cigarettes: A Randomized Crossover Pilot Study". Determination of the acute pulmonary toxicities of e-cigarettes in young adults is of major public health importance, as e-cigarette vapor contains established toxicants that as hypothesized cause acute damage to the airways and the pulmonary microvasculature that may promote the development of CLD,...
What is the current status of trial NCT02783768?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 12 participants. The study started on 2017-03-01. Estimated completion is 2018-07-24.
What interventions are being tested in trial NCT02783768?
The interventions under investigation include: Sham (OTHER), Gadolinium (DRUG), E-cigarette (DEVICE), Hyperpolarized 3-Helium (DRUG).
Who is sponsoring clinical trial NCT02783768?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
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