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NCT02780297 · ClinicalTrials.gov registry record

Prospective Research Rare Kidney Stones (ProRKS)

A clinical trial of Dent Disease and Cystinuria, sponsored by Mayo Clinic.

Recruiting
Registry status
220
Enrollment target
11
Study locations

NCT02780297 is a study of Dent Disease and Cystinuria that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 220 participants, below the 723-participant average among 4 other Dent Disease trials with a reported enrollment target (70% lower). The trial reports 11 study locations across 10 states.

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The verdict

NCT02780297, a study of Dent Disease and Cystinuria, is actively recruiting participants, sponsored by Mayo Clinic.

RECRUITING
Registry status
220 participants
Enrollment target
11
Study locations

Study Summary

The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of renal dysfunction in these disorders.

Study Locations (11)

Other

  • Landspitali Universtiy Hospital - Reykjavik
  • Shaare Zedek Medica Center - Jerusalem

Alabama

  • University of Alabama @ Birmingham - Birmingham

Florida

  • Mayo Clinic Jacksonville - Jacksonville

Illinois

  • Children's Memorial Hospital - Chicago

Massachusetts

  • Children's Hospital, Harvard Medical School - Boston

Minnesota

  • Mayo Clinic Hyperoxaluria Center - Rochester

New York

  • New York University - New York

Ohio

  • Cincinnati Children's Hosptial Medical Center - Cincinnati

Trial Details

FieldValue
Enrollment Target 220 participants
Start Date 2016-05
Est. Completion 2026-07

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT02780297

The ClinicalTrials.gov registry entry for NCT02780297 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 220 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 723-participant average among 4 other Dent Disease trials with a reported enrollment target (70% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Dent Disease appearing as the primary indexed condition, and to 0 interventions.

NCT02780297 reports 11 study locations spanning 10 distinct geographic areas - top geographies include Other, Alabama, Florida.

Frequently Asked Questions

What is clinical trial NCT02780297 about?

NCT02780297 is a clinical study titled "Prospective Research Rare Kidney Stones (ProRKS)". The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The invest...

What is the current status of trial NCT02780297?

This trial is currently recruiting. The enrollment target is 220 participants. The study started on 2016-05. Estimated completion is 2026-07.

What conditions does trial NCT02780297 study?

This clinical trial studies the following conditions: Dent Disease, Cystinuria, Hyperoxaluria, Lowe Syndrome, Adenine Phosphoribosyltransferase Deficiency.

Who is sponsoring clinical trial NCT02780297?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02780297 being conducted?

This trial has 11 study locations across Alabama, Florida, Illinois, Massachusetts, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.