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NCT02780297 · ClinicalTrials.gov registry record
Prospective Research Rare Kidney Stones (ProRKS)
A clinical trial of Dent Disease and Cystinuria, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- 220
- Enrollment target
- 11
- Study locations
NCT02780297: Recruiting study of Dent Disease and Cystinuria, sponsored by Mayo Clinic.
NCT02780297 is a study of Dent Disease and Cystinuria that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 220 participants, below the 723-participant average among 4 other Dent Disease trials with a reported enrollment target (70% lower). The trial reports 11 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02780297, a study of Dent Disease and Cystinuria, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- 220 participants
- Enrollment target
- 11
- Study locations
Study Summary
The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of renal dysfunction in these disorders.
Primary Outcome
Statistically significant changes (increase or decrease) in inflammatory urinary biomarkers compared to reference values
Conditions Studied
Study Locations (11)
Other
- Landspitali Universtiy Hospital - Reykjavik
- Shaare Zedek Medica Center - Jerusalem
Alabama
- University of Alabama @ Birmingham - Birmingham
Florida
- Mayo Clinic Jacksonville - Jacksonville
Illinois
- Children's Memorial Hospital - Chicago
Massachusetts
- Children's Hospital, Harvard Medical School - Boston
Minnesota
- Mayo Clinic Hyperoxaluria Center - Rochester
New York
- New York University - New York
Ohio
- Cincinnati Children's Hosptial Medical Center - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 220 participants |
| Start Date | 2016-05 |
| Est. Completion | 2026-07 |
What NCT02780297 shows while recruiting
NCT02780297 is an observational study that tracks outcomes without assigning an intervention. The registered 220 participants enrollment target is mid-sized for trials with a published cap, below the 723-participant average among 4 other Dent Disease trials with a reported enrollment target (70% lower).
The record links to 5 conditions, with Dent Disease appearing as the primary indexed condition, and to 0 interventions.
NCT02780297 lists 11 locations in 10 states (Other, Alabama, Florida).
Frequently Asked Questions
What is clinical trial NCT02780297 about?
NCT02780297 is a clinical study titled "Prospective Research Rare Kidney Stones (ProRKS)". The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The invest...
What is the current status of trial NCT02780297?
This trial is currently recruiting. The enrollment target is 220 participants. The study started on 2016-05. Estimated completion is 2026-07.
What conditions does trial NCT02780297 study?
This clinical trial studies the following conditions: Dent Disease, Cystinuria, Hyperoxaluria, Lowe Syndrome, Adenine Phosphoribosyltransferase Deficiency.
Who is sponsoring clinical trial NCT02780297?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02780297 being conducted?
This trial has 11 study locations across Alabama, Florida, Illinois, Massachusetts, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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