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NCT02778750 · ClinicalTrials.gov registry record

Evaluation Of The Pan-microbiome and Host Immune Response in CF

A clinical trial, sponsored by NYU Langone Health.

Completed
Registry status
12
Enrollment target

NCT02778750 is a clinical trial that has completed, run by NYU Langone Health. The registered enrollment target is 12 participants.

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The verdict

NCT02778750 has completed, sponsored by NYU Langone Health.

COMPLETED
Registry status
12 participants
Enrollment target

Study Summary

Investigators will examine temporal and regional dynamic changes in the microbiome of Cystic Fibrosis patients to explore microbiome features that are associated with an inflammatory phenotype. Investigators hypothesize that temporal and spatial differences in lung microbiome are associated with host inflammatory responses. While chronic and polymicrobial airway colonization are commonly recognized in cystic fibrosis (CF), it is unclear what factors of the microbial environment lead to infection with pathogenic microorganism. This is a multi center, longitudinal cohort of adult Cystic Fibrosis subjects recruit4ed from NYU and Columbia to understand how changes in the airway microbiome may affect the host inflammatory responses in Cystic Fibrosis (CF). There will be three approaches to understanding inflammatory responses; 1) a longitudinal assessment of temporal changes in the microbiome over a 6-month period of clinical stability; 2) comparison of the regional differences in airway microbiome between lung segments with more versus less disease; 3) evaluation of functional aspects of the lung microbiome.

Interventions

  • PROCEDURE Two-Bronchoscope Technique

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2015-06-05
Est. Completion 2020-03-12

Sponsor

NYU Langone Health

1,164 total trials

What the Registry Record Tells You About NCT02778750

The ClinicalTrials.gov registry entry for NCT02778750 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NYU Langone Health, which has 1,164 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Two-Bronchoscope Technique is the first listed.

NCT02778750 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02778750 about?

NCT02778750 is a clinical study titled "Evaluation Of The Pan-microbiome and Host Immune Response in CF". Investigators will examine temporal and regional dynamic changes in the microbiome of Cystic Fibrosis patients to explore microbiome features that are associated with an inflammatory phenotype. Investigators hypothesize that temporal and spatial differences in lung microbiome are associated with hos...

What is the current status of trial NCT02778750?

This trial is currently completed. The enrollment target is 12 participants. The study started on 2015-06-05. Estimated completion is 2020-03-12.

What interventions are being tested in trial NCT02778750?

The interventions under investigation include: Two-Bronchoscope Technique (PROCEDURE).

Who is sponsoring clinical trial NCT02778750?

This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.