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NCT02775695 · ClinicalTrials.gov registry record · Phase 2
Efficacy of Doxycycline on Metakaryote Cell Death in Patients With Resectable Pancreatic Cancer
A Phase 2 study, sponsored by Medical College of Wisconsin.
- Completed
- Registry status
- Phase 2
- Development phase
- 12
- Enrollment target
NCT02775695: Completed Phase 2 study, sponsored by Medical College of Wisconsin.
NCT02775695 is a Phase 2 study that has completed, run by Medical College of Wisconsin. The registered enrollment target is 12 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02775695, a Phase 2 study, has completed, sponsored by Medical College of Wisconsin.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 12 participants
- Enrollment target
Study Summary
This is a window-of-opportunity study that examines the efficacy of doxycycline, and FDA-approved oral antibiotic, on metakaryotic (cancer stem cells) in resectable pancreatic cancer following eight weeks of treatment.
Primary Outcome
The histopathologic response of the primary tumor will be assessed using the College of American Pathology criteria for residual tumor response following neoadjuvant therapy for the exocrine pancreas. Researchers will enumerate the number of observed dead/dying metakaryotes per 1 gram of resected pancreatic tissue.
Interventions
- DRUG Doxycycline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2017-04-03 |
| Est. Completion | 2022-05-26 |
| Phase | Phase 2 |
What the finished NCT02775695 record still lists
NCT02775695 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 1 intervention - of which Doxycycline is the first listed.
NCT02775695 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02775695 about?
NCT02775695 is a clinical study titled "Efficacy of Doxycycline on Metakaryote Cell Death in Patients With Resectable Pancreatic Cancer". This is a window-of-opportunity study that examines the efficacy of doxycycline, and FDA-approved oral antibiotic, on metakaryotic (cancer stem cells) in resectable pancreatic cancer following eight weeks of treatment.
What is the current status of trial NCT02775695?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2017-04-03. Estimated completion is 2022-05-26.
What interventions are being tested in trial NCT02775695?
The interventions under investigation include: Doxycycline (DRUG).
Who is sponsoring clinical trial NCT02775695?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02775695's enrollment target sits among peer trials
12 1948th of 2000 higher than 34 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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