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NCT02772367 · ClinicalTrials.gov registry record
Generation of Heart Muscle Cells From Blood or Skin Cells of Breast Cancer Patients
A clinical trial of Breast Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- 120
- Enrollment target
- 1
- Study location
NCT02772367: Recruiting study of Breast Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
NCT02772367 is a study of Breast Cancer that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 120 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02772367, a study of Breast Cancer, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate whether cells from a biopsy taken from the patient skin can be transformed into cardiomyocytes the changes in cardiomyocyte (heart muscle cells) when grown in a special culture medium outside of the body. The structure and function of these cells will then be studied to determine why some patients with breast cancer who are treated with chemotherapy including anthracycline (e.g. Doxorubicin) and anti-HER2 therapy (e.g. Herceptin) develop decreased heart function.
Primary Outcome
described by Yamanaka et al with modification using the Millipore STEMCCA excisable polycystronic lentivirus reprogramming kit.2
Conditions Studied
Interventions
- PROCEDURE skin punch biopsy
Study Locations (1)
New York
- Memorial Sloan-Kettering Cancer Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2016-05-11 |
| Est. Completion | 2026-05 |
What NCT02772367 shows while recruiting
NCT02772367 is an observational study that tracks outcomes without assigning an intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which skin punch biopsy is the first listed.
NCT02772367 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT02772367 about?
NCT02772367 is a clinical study titled "Generation of Heart Muscle Cells From Blood or Skin Cells of Breast Cancer Patients". The purpose of this study is to investigate whether cells from a biopsy taken from the patient skin can be transformed into cardiomyocytes the changes in cardiomyocyte (heart muscle cells) when grown in a special culture medium outside of the body. The structure and function of these cells will then...
What is the current status of trial NCT02772367?
This trial is currently recruiting. The enrollment target is 120 participants. The study started on 2016-05-11. Estimated completion is 2026-05.
What conditions does trial NCT02772367 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT02772367?
The interventions under investigation include: skin punch biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT02772367?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02772367 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02772367's enrollment target sits among peer trials
120 510th of 1224 higher than 703 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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