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NCT02752789 · ClinicalTrials.gov registry record
Impact of Allo- and Autoantibodies on Chronic Cardiac Allograft Function
A clinical trial of Pediatric Heart Transplantation and Pediatric Heart Transplant Recipients, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Completed
- Registry status
- 407
- Enrollment target
- 9
- Study locations
NCT02752789: Completed study of Pediatric Heart Transplantation and Pediatric Heart Transplant Recipients, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
NCT02752789 is a study of Pediatric Heart Transplantation and Pediatric Heart Transplant Recipients that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 407 participants. The trial reports 9 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02752789, a study of Pediatric Heart Transplantation and Pediatric Heart Transplant Recipients, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- COMPLETED
- Registry status
- 407 participants
- Enrollment target
- 9
- Study locations
Study Summary
This is a multi-center, prospective, single cohort, observational study of pediatric heart transplant recipients designed to determine the impact of preformed versus de novo human leukocyte antigen (HLA) donor-specific antibodies (DSA), and antibodies to the self-antigens cardiac myosin and vimentin, on chronic allograft function. In addition, the investigators will explore mechanisms of action and predictors of DSA, rejection and altered pathophysiology.
Conditions Studied
Study Locations (9)
New York
- Columbia University Medical Center - New York
- Children's Hospital at Montefiore - New York
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
- Children's Hospital of Pittsburgh - Pittsburgh
Georgia
- Emory University School of Medicine - Atlanta
Massachusetts
- Children's Hospital Boston - Boston
Missouri
- St. Louis Children's Hospital - St Louis
Tennessee
- Monroe Carell Jr. Children's Hospital - Nashville
Other
- Hospital for Sick Children - Toronto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 407 participants |
| Start Date | 2014-07-15 |
| Est. Completion | 2019-11-01 |
What the finished NCT02752789 record still lists
NCT02752789 is an observational study that tracks outcomes without assigning an intervention. The registered 407 participants enrollment target is mid-sized for trials with a published cap.
The record links to 2 conditions, with Pediatric Heart Transplantation appearing as the primary indexed condition, and to 0 interventions.
NCT02752789 lists 9 locations in 7 states (New York, Pennsylvania, Georgia).
Frequently Asked Questions
What is clinical trial NCT02752789 about?
NCT02752789 is a clinical study titled "Impact of Allo- and Autoantibodies on Chronic Cardiac Allograft Function". This is a multi-center, prospective, single cohort, observational study of pediatric heart transplant recipients designed to determine the impact of preformed versus de novo human leukocyte antigen (HLA) donor-specific antibodies (DSA), and antibodies to the self-antigens cardiac myosin and vimentin...
What is the current status of trial NCT02752789?
This trial is currently completed. The enrollment target is 407 participants. The study started on 2014-07-15. Estimated completion is 2019-11-01.
What conditions does trial NCT02752789 study?
This clinical trial studies the following conditions: Pediatric Heart Transplantation, Pediatric Heart Transplant Recipients.
Who is sponsoring clinical trial NCT02752789?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02752789 being conducted?
This trial has 9 study locations across Georgia, Massachusetts, Missouri, New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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