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NCT02740114 · ClinicalTrials.gov registry record · Phase 3
Wound Infiltration With Liposomal Bupivacaine vs. Standard Wound Infiltration With Bupivacaine in Patient's Undergoing Open Gynecologic Surgery on an Enhanced Recovery Pathway
A Phase 3 study, sponsored by M.D. Anderson Cancer Center.
- Terminated
- Registry status
- Phase 3
- Development phase
- 105
- Enrollment target
NCT02740114: Clinical Trial Phase 3 study, sponsored by M.D. Anderson Cancer Center.
NCT02740114 is a Phase 3 study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 105 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02740114, a Phase 3 study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 105 participants
- Enrollment target
Study Summary
Bupivacaine is a drug that is traditionally given as an injection to numb surgical sites. Liposomes are molecules that are similar to fats. Sometimes drugs are combined with liposomes to make them able to stay in the body for longer periods of time. This has been done with bupivacaine to create liposomal bupivacaine. The goal of this clinical research study is to compare the effects of bupivacaine to those of liposomal bupivacaine when given to patients who are having gynecologic surgery. Researchers want to compare how long the drugs work to numb the wound and how long patients take to recover from surgery.
Primary Outcome
Treatment arms compared with respect to the proportion of patients opioid-free at 48 hours using the Cochran-Mantel-Haenszel test stratified by surgeon.
Interventions
- DRUG Bupivacaine
- DRUG Liposomal Bupivacaine
- DRUG Oxycodone
- BEHAVIORAL Symptom Questionnaire
- BEHAVIORAL Pill Diary
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2016-08-31 |
| Est. Completion | 2020-07-23 |
| Phase | Phase 3 |
Why NCT02740114 stopped before completion
NCT02740114 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 5 interventions - of which Bupivacaine is the first listed.
NCT02740114 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02740114 about?
NCT02740114 is a clinical study titled "Wound Infiltration With Liposomal Bupivacaine vs. Standard Wound Infiltration With Bupivacaine in Patient's Undergoing Open Gynecologic Surgery on an Enhanced Recovery Pathway". Bupivacaine is a drug that is traditionally given as an injection to numb surgical sites. Liposomes are molecules that are similar to fats. Sometimes drugs are combined with liposomes to make them able to stay in the body for longer periods of time. This has been done with bupivacaine to create lipo...
What is the current status of trial NCT02740114?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 105 participants. The study started on 2016-08-31. Estimated completion is 2020-07-23.
What interventions are being tested in trial NCT02740114?
The interventions under investigation include: Bupivacaine (DRUG), Liposomal Bupivacaine (DRUG), Oxycodone (DRUG), Symptom Questionnaire (BEHAVIORAL), Pill Diary (BEHAVIORAL).
Who is sponsoring clinical trial NCT02740114?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02740114's enrollment target sits among peer trials
105 1670th of 2000 higher than 330 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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