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NCT02732015 · ClinicalTrials.gov registry record · Phase 2

Rolapitant Hydrochloride in Preventing Nausea/Vomiting in Patients With Sarcoma Receiving Chemotherapy

A Phase 2 study, sponsored by M.D. Anderson Cancer Center.

Terminated
Registry status
Phase 2
Development phase
37
Enrollment target

NCT02732015: Clinical Trial Phase 2 study, sponsored by M.D. Anderson Cancer Center.

NCT02732015 is a Phase 2 study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 37 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02732015, a Phase 2 study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.

TERMINATED
Registry status
Phase 2
Development phase
37 participants
Enrollment target

Study Summary

This randomized phase II trial studies how well rolapitant hydrochloride works in preventing nausea/vomiting in patients with sarcoma receiving chemotherapy. Antiemetic drugs, such as rolapitant hydrochloride, may help control or prevent nausea and vomiting in patients treated with chemotherapy.

Primary Outcome

Complete response (CR) no emetic episodes and no rescue medications.

Interventions

  • DRUG Doxorubicin
  • OTHER Laboratory Biomarker Analysis
  • DRUG Dexamethasone
  • DRUG Ifosfamide
  • DRUG Fosaprepitant Dimeglumine

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2016-10-12
Est. Completion 2020-07-10
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

Why NCT02732015 stopped before completion

NCT02732015 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (72% lower).

The record links to 0 conditions, and to 5 interventions - of which Doxorubicin is the first listed.

NCT02732015 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02732015 about?

NCT02732015 is a clinical study titled "Rolapitant Hydrochloride in Preventing Nausea/Vomiting in Patients With Sarcoma Receiving Chemotherapy". This randomized phase II trial studies how well rolapitant hydrochloride works in preventing nausea/vomiting in patients with sarcoma receiving chemotherapy. Antiemetic drugs, such as rolapitant hydrochloride, may help control or prevent nausea and vomiting in patients treated with chemotherapy.

What is the current status of trial NCT02732015?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 37 participants. The study started on 2016-10-12. Estimated completion is 2020-07-10.

What interventions are being tested in trial NCT02732015?

The interventions under investigation include: Doxorubicin (DRUG), Laboratory Biomarker Analysis (OTHER), Dexamethasone (DRUG), Ifosfamide (DRUG), Fosaprepitant Dimeglumine (DRUG).

Who is sponsoring clinical trial NCT02732015?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02732015's enrollment target sits among peer trials

37 1484th of 2000 higher than 505 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02732015, the US trial registry maintained by the National Library of Medicine. NCT02732015 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.