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NCT02702635 · ClinicalTrials.gov registry record · NA
Measuring Blood Flow Characteristics Using Dynamic Contrast Enhanced Magnetic Resonance Imaging
A NA study, sponsored by Loma Linda University.
- Completed
- Registry status
- NA
- Development phase
- 53
- Enrollment target
NCT02702635: Completed NA study, sponsored by Loma Linda University.
NCT02702635 is a NA study that has completed, run by Loma Linda University. The registered enrollment target is 53 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02702635, a NA study, has completed, sponsored by Loma Linda University.
- COMPLETED
- Registry status
- NA
- Development phase
- 53 participants
- Enrollment target
Study Summary
Dynamic contrast-enhanced (DCE) MRI gives quantitative and semi-quantitative information about the integrity of the vascular system and can be used to quantify blood-brain barrier (BBB) integrity. The BBB plays a pathophysiological role in diabetes, cognitive disorders such as mild cognitive impairment, Alzheimer's disease, multiple sclerosis, and chronic traumatic encephalopathy. Although dysfunctional, changes in BBB integrity for these conditions are thought to be subtle and close to intact values. Recent studies have shown it is possible measure small changes in the BBB integrity as an early sign of disease using DCE MRI. The objective of this study is to apply an optimized DCE imaging protocol and novel image post-processing to obtain new information about the BBB integrity in aging. These techniques show promise for both improving clinical diagnosis, and elucidated the physiology or various disease processes.
Interventions
- PROCEDURE DCE MRI of the brain
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 53 participants |
| Start Date | 2015-09-15 |
| Est. Completion | 2021-05-26 |
| Phase | NA |
What the finished NCT02702635 record still lists
NCT02702635 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 53 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which DCE MRI of the brain is the first listed.
NCT02702635 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02702635 about?
NCT02702635 is a clinical study titled "Measuring Blood Flow Characteristics Using Dynamic Contrast Enhanced Magnetic Resonance Imaging". Dynamic contrast-enhanced (DCE) MRI gives quantitative and semi-quantitative information about the integrity of the vascular system and can be used to quantify blood-brain barrier (BBB) integrity. The BBB plays a pathophysiological role in diabetes, cognitive disorders such as mild cognitive impairm...
What is the current status of trial NCT02702635?
This trial is currently completed. It is a NA study. The enrollment target is 53 participants. The study started on 2015-09-15. Estimated completion is 2021-05-26.
What interventions are being tested in trial NCT02702635?
The interventions under investigation include: DCE MRI of the brain (PROCEDURE).
Who is sponsoring clinical trial NCT02702635?
This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02702635's enrollment target sits among peer trials
53 1271st of 2000 higher than 729 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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