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NCT02702635 · ClinicalTrials.gov registry record · NA

Measuring Blood Flow Characteristics Using Dynamic Contrast Enhanced Magnetic Resonance Imaging

A NA study, sponsored by Loma Linda University.

Completed
Registry status
NA
Development phase
53
Enrollment target

NCT02702635 is a NA study that has completed, run by Loma Linda University. The registered enrollment target is 53 participants.

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The verdict

NCT02702635, a NA study, has completed, sponsored by Loma Linda University.

COMPLETED
Registry status
NA
Development phase
53 participants
Enrollment target

Study Summary

Dynamic contrast-enhanced (DCE) MRI gives quantitative and semi-quantitative information about the integrity of the vascular system and can be used to quantify blood-brain barrier (BBB) integrity. The BBB plays a pathophysiological role in diabetes, cognitive disorders such as mild cognitive impairment, Alzheimer's disease, multiple sclerosis, and chronic traumatic encephalopathy. Although dysfunctional, changes in BBB integrity for these conditions are thought to be subtle and close to intact values. Recent studies have shown it is possible measure small changes in the BBB integrity as an early sign of disease using DCE MRI. The objective of this study is to apply an optimized DCE imaging protocol and novel image post-processing to obtain new information about the BBB integrity in aging. These techniques show promise for both improving clinical diagnosis, and elucidated the physiology or various disease processes.

Interventions

  • PROCEDURE DCE MRI of the brain

Trial Details

FieldValue
Enrollment Target 53 participants
Start Date 2015-09-15
Est. Completion 2021-05-26
Phase NA

Sponsor

Loma Linda University

237 total trials

What the Registry Record Tells You About NCT02702635

The ClinicalTrials.gov registry entry for NCT02702635 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 53 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Loma Linda University, which has 237 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which DCE MRI of the brain is the first listed.

NCT02702635 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02702635 about?

NCT02702635 is a clinical study titled "Measuring Blood Flow Characteristics Using Dynamic Contrast Enhanced Magnetic Resonance Imaging". Dynamic contrast-enhanced (DCE) MRI gives quantitative and semi-quantitative information about the integrity of the vascular system and can be used to quantify blood-brain barrier (BBB) integrity. The BBB plays a pathophysiological role in diabetes, cognitive disorders such as mild cognitive impairm...

What is the current status of trial NCT02702635?

This trial is currently completed. It is a NA study. The enrollment target is 53 participants. The study started on 2015-09-15. Estimated completion is 2021-05-26.

What interventions are being tested in trial NCT02702635?

The interventions under investigation include: DCE MRI of the brain (PROCEDURE).

Who is sponsoring clinical trial NCT02702635?

This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.