Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02666508 · ClinicalTrials.gov registry record · NA

Trial of Toothpaste to Reduce Plaque and Inflammation

A NA study, sponsored by University of Illinois at Chicago.

Completed
Registry status
NA
Development phase
61
Enrollment target

NCT02666508: Completed NA study, sponsored by University of Illinois at Chicago.

NCT02666508 is a NA study that has completed, run by University of Illinois at Chicago. The registered enrollment target is 61 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02666508, a NA study, has completed, sponsored by University of Illinois at Chicago.

COMPLETED
Registry status
NA
Development phase
61 participants
Enrollment target

Study Summary

Dental plaque causes caries and periodontal disease and data are sparse about toothpaste and plaque removal. Inflammation, caused by dental plaque, is a risk factor for cardiovascular disease. (CVD) The availability of (Plaque HD (TM), a plaque identifying toothpaste with targetol technology (TM)), afforded the unique opportunity to test whether there were statistically significant and clinically important reductions in plaque and inflammation in a randomized trial of apparently healthy individuals.

Primary Outcome

Measure description "percentage" refers to the change in plaque percentage from the baseline to the follow-up visit. The follow-up visit occurred between 30 and 60 days post baseline.

Interventions

  • OTHER Plaque identifying toothpaste
  • OTHER Non-plaque identifying toothpaste

Trial Details

FieldValue
Enrollment Target 61 participants
Start Date 2015-09-01
Est. Completion 2016-08-22
Phase NA
University of Illinois at Chicago

430 total trials

What the finished NCT02666508 record still lists

NCT02666508 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which Plaque identifying toothpaste is the first listed.

NCT02666508 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02666508 about?

NCT02666508 is a clinical study titled "Trial of Toothpaste to Reduce Plaque and Inflammation". Dental plaque causes caries and periodontal disease and data are sparse about toothpaste and plaque removal. Inflammation, caused by dental plaque, is a risk factor for cardiovascular disease. (CVD) The availability of (Plaque HD (TM), a plaque identifying toothpaste with targetol technology (TM)), ...

What is the current status of trial NCT02666508?

This trial is currently completed. It is a NA study. The enrollment target is 61 participants. The study started on 2015-09-01. Estimated completion is 2016-08-22.

What interventions are being tested in trial NCT02666508?

The interventions under investigation include: Plaque identifying toothpaste (OTHER), Non-plaque identifying toothpaste (OTHER).

Who is sponsoring clinical trial NCT02666508?

This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02666508's enrollment target sits among peer trials

61 1164th of 2000 higher than 837 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04115306 · 61 participants · Phase 1

    Phase 1/1b/2 Study of Oral PMD-026 in Patients With Metastatic Breast Cancer

  • NCT05070845 · 61 participants · Phase 2

    Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia

  • NCT05187832 · 61 participants · Phase 1

    A Study of AND019 in Women With ER Positive HER2 Negative Advanced or Metastatic Breast Cancer

  • NCT05269316 · 61 participants · Phase 1

    Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT02666508, the US trial registry maintained by the National Library of Medicine. NCT02666508 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.