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NCT02656381 · ClinicalTrials.gov registry record

Uveitis/Intraocular Inflammatory Disease Biobank (iBank)

A clinical trial, sponsored by National Eye Institute (NEI).

Completed
Registry status
343
Enrollment target

NCT02656381: Completed study, sponsored by National Eye Institute (NEI).

NCT02656381 is a clinical trial that has completed, run by National Eye Institute (NEI). The registered enrollment target is 343 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02656381 has completed, sponsored by National Eye Institute (NEI).

COMPLETED
Registry status
343 participants
Enrollment target

Study Summary

Background: Uveitis is a serious eye disease that can cause vision loss. Treatment sometimes causes serious side effects or does not work. Researchers want to learn more about uveitis and why some people develop it. Objective: To learn clinical and genetic factors that may make people develop uveitis and influence how they respond to treatment. Eligibility: People ages 8 and older who have uveitis, scleritis, inflammatory eye disease, or a disease related to eye inflammation INCLUSION CRITERIA FOR COVID-19 COHORT: Participants with COVID-19 will be eligible if they: 1. Have a diagnosis of COVID-19 confirmed by a nasaopharyngeal swab (or another confirmative test) within less than or equal to 3 days prior, with symptoms of any severity. 2. Are able to give verbal consent. 3. Are 16 years of age or older. EXCLUSION CRITERIA FOR COVID-19 COHORT: Participants with COVID-19 will not be eligible if they: 1. Use regular prescription eye drops on the day of sampling. 2. Current use of antiviral medications. Design: Participants will be screened with: Medical history Physical exam Eye exam Participation lasts up to 10 years. The clinic visit schedule varies depending on participants eye disease: Baseline visit with annual follow-ups Baseline visit, visits at months 3 and 6, and annual follow-ups Another schedule set by the researcher Depending on participants eye disease, tests during each visit could include: Fluorescein angiography or indocyanine green angiography: Dye is injected through a needle in the arm and flows through the blood vessels in the eye. A camera takes pictures of the eye. Electroretinography: Participants sit in the dark with their eyes patched. After 30 minutes, numbing drops and contact lenses are put in the eyes. Then, the retina is stimulated with flashing lights. Perimetry: Participants look into a bowl or lens and press a button when they see a light. Conjunctival or corneal biopsy, or skin biopsy: A small piece of tissue

Primary Outcome

The intent is to collect data on a variety of phenotypic pararmeters and to store biospecimens in a manner that permits a broad array of potnential testing and experimentation in the future.

Trial Details

FieldValue
Enrollment Target 343 participants
Start Date 2016-07-26
Est. Completion 2023-05-04
National Eye Institute (NEI)

221 total trials

What the finished NCT02656381 record still lists

NCT02656381 is an observational study that tracks outcomes without assigning an intervention. The registered 343 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 0 interventions.

NCT02656381 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02656381 about?

NCT02656381 is a clinical study titled "Uveitis/Intraocular Inflammatory Disease Biobank (iBank)". Background: Uveitis is a serious eye disease that can cause vision loss. Treatment sometimes causes serious side effects or does not work. Researchers want to learn more about uveitis and why some people develop it. Objective: To learn clinical and genetic factors that may make people develop uve...

What is the current status of trial NCT02656381?

This trial is currently completed. The enrollment target is 343 participants. The study started on 2016-07-26. Estimated completion is 2023-05-04.

Who is sponsoring clinical trial NCT02656381?

This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT02656381, the US trial registry maintained by the National Library of Medicine. NCT02656381 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.