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NCT02653638 · ClinicalTrials.gov registry record · Early Phase 1
Blood Brain Flow and Exercise
A Early Phase 1 study, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 80
- Enrollment target
NCT02653638: Completed Early Phase 1 study, sponsored by University of Wisconsin, Madison.
NCT02653638 is a Early Phase 1 study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 80 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (51% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02653638, a Early Phase 1 study, has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 80 participants
- Enrollment target
Study Summary
Cerebral vasodilator responses to CO2 will be measured in young healthy adults, healthy sedentary older adults, and healthy exercise trained older adults. This variable will be examined before and after administering the cyclooxygenase inhibitor indomethacin, which has been shown to blunt cerebral vasodilator responses. In addition, the investigators will examine these counter-regulatory hemodynamic mechanisms to hypoperfusion caused by indomethacin.
Primary Outcome
Utilize a Transcranial Doppler to measure blood flow velocity in response to inhaled carbon dioxide.
Interventions
- OTHER Control
- DRUG Indomethacin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2016-06 |
| Est. Completion | 2019-04 |
| Phase | Early Phase 1 |
What the finished NCT02653638 record still lists
NCT02653638 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (51% higher).
The record links to 0 conditions, and to 2 interventions - of which Control is the first listed.
NCT02653638 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02653638 about?
NCT02653638 is a clinical study titled "Blood Brain Flow and Exercise". Cerebral vasodilator responses to CO2 will be measured in young healthy adults, healthy sedentary older adults, and healthy exercise trained older adults. This variable will be examined before and after administering the cyclooxygenase inhibitor indomethacin, which has been shown to blunt cerebral v...
What is the current status of trial NCT02653638?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 80 participants. The study started on 2016-06. Estimated completion is 2019-04.
What interventions are being tested in trial NCT02653638?
The interventions under investigation include: Control (OTHER), Indomethacin (DRUG).
Who is sponsoring clinical trial NCT02653638?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02653638's enrollment target sits among peer trials
80 271st of 2000 higher than 1,704 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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