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COMPLETED Phase 2

A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)

NCT02637557 · View on ClinicalTrials.gov ↗

Study Summary

The objectives of this study are to evaluate the safety, efficacy, and dose-response relationship of IW-3718 administered orally to participants who have GERD and continue to experience GERD symptoms while receiving once-daily (QD), standard-dose proton pump inhibitors (PPIs).

Interventions

  • DRUG Matching Placebo
  • DRUG IW-3718
  • DRUG PPI

Study Locations (20)

California

  • IW-3718 Investigator — Anaheim
  • IW-3718 Investigator — Carmichael
  • IW-3718 Investigator — Chula Vista
  • IW-3718 Investigator — La Mirada
  • IW-3718 Investigator — Mission Hills
  • IW-3718 Investigator — Newport Beach
  • IW-3718 Investigator — Oakland
  • IW-3718 Investigator — Sacramento
  • IW-3718 Investigator — San Diego

Arizona

  • IW-3718 Investigator — Phoenix
  • IW-3718 Investigator — Tucson
  • IW-3718 Investigator — Tucson
  • IW-3718 Investigator — Tucson

Florida

  • IW-3718 Investigator — DeLand
  • IW-3718 Investigator — Hollywood
  • IW-3718 Investigator — Inverness

Connecticut

  • IW-3718 Investigator — Bristol
  • IW-3718 Investigator — Waterbury

Alabama

  • IW-3718 Investigator — Dothan

Arkansas

  • IW-3718 Investigator — North Little Rock

Trial Details

FieldValue
Enrollment Target 282 participants
Start Date 2016-03-01
Est. Completion 2017-04-26
Phase Phase 2

Sponsor

Ironwood Pharmaceuticals

5 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02637557

The ClinicalTrials.gov registry entry for NCT02637557 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 282 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ironwood Pharmaceuticals, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Gastroesophageal Reflux Disease appearing as the primary indexed condition, and to 3 interventions — of which Matching Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02637557 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, Arizona, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02637557 about?

NCT02637557 is a clinical study titled "A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)". The objectives of this study are to evaluate the safety, efficacy, and dose-response relationship of IW-3718 administered orally to participants who have GERD and continue to experience GERD symptoms while receiving once-daily (QD), standard-dose proton pump inhibitors (PPIs).

What is the current status of trial NCT02637557?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 282 participants. The study started on 2016-03-01. Estimated completion is 2017-04-26.

What conditions does trial NCT02637557 study?

This clinical trial studies the following conditions: Gastroesophageal Reflux Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02637557?

The interventions under investigation include: Matching Placebo (DRUG), IW-3718 (DRUG), PPI (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02637557?

This trial is sponsored by Ironwood Pharmaceuticals, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02637557 being conducted?

This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial