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NCT02621151 · ClinicalTrials.gov registry record · Phase 2

Pembrolizumab (MK3475), Gemcitabine, and Concurrent Hypofractionated Radiation Therapy for Muscle-Invasive Urothelial Cancer of the Bladder

A Phase 2 study of Muscle-invasive Urothelial Cancer of the Bladder, sponsored by NYU Langone Health.

Active
Registry status
Phase 2
Development phase
60
Enrollment target
5
Study locations

NCT02621151 is a Phase 2 study of Muscle-invasive Urothelial Cancer of the Bladder that is active but no longer recruiting, run by NYU Langone Health. The registered enrollment target is 60 participants. The trial reports 5 study locations across 4 states.

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The verdict

NCT02621151, a Phase 2 study of Muscle-invasive Urothelial Cancer of the Bladder, is active but no longer recruiting, sponsored by NYU Langone Health.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target
5
Study locations

Study Summary

This trial is to assess the efficacy of pembrolizumab (MK3475) added to concurrent radiation and gemcitabine in the management of patients with muscle-invasive urothelial cancer who are not candidates for or decline radical cystectomy.

Interventions

  • BIOLOGICAL Pembrolizumab
  • RADIATION External Beam Radiation Therapy
  • DRUG Gemcitabine
  • PROCEDURE Transurethral Resection of Bladder Tumor

Study Locations (5)

New York

  • NYU Perlmutter Cancer Center - New York
  • Memorial Sloan Kettering - New York

Illinois

  • University of Chicago - Chicago

Michigan

  • University of Michigan Health System - Ann Arbor

North Carolina

  • University of North Carolina - Chapel Hill

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2016-08-11
Est. Completion 2025-12
Phase Phase 2

Sponsor

NYU Langone Health

1,164 total trials

What the Registry Record Tells You About NCT02621151

The ClinicalTrials.gov registry entry for NCT02621151 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NYU Langone Health, which has 1,164 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Muscle-invasive Urothelial Cancer of the Bladder appearing as the primary indexed condition, and to 4 interventions - of which Pembrolizumab is the first listed.

NCT02621151 reports 5 study locations spanning 4 distinct geographic areas - top geographies include New York, Illinois, Michigan.

Frequently Asked Questions

What is clinical trial NCT02621151 about?

NCT02621151 is a clinical study titled "Pembrolizumab (MK3475), Gemcitabine, and Concurrent Hypofractionated Radiation Therapy for Muscle-Invasive Urothelial Cancer of the Bladder". This trial is to assess the efficacy of pembrolizumab (MK3475) added to concurrent radiation and gemcitabine in the management of patients with muscle-invasive urothelial cancer who are not candidates for or decline radical cystectomy.

What is the current status of trial NCT02621151?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2016-08-11. Estimated completion is 2025-12.

What conditions does trial NCT02621151 study?

This clinical trial studies the following conditions: Muscle-invasive Urothelial Cancer of the Bladder.

What interventions are being tested in trial NCT02621151?

The interventions under investigation include: Pembrolizumab (BIOLOGICAL), External Beam Radiation Therapy (RADIATION), Gemcitabine (DRUG), Transurethral Resection of Bladder Tumor (PROCEDURE).

Who is sponsoring clinical trial NCT02621151?

This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02621151 being conducted?

This trial has 5 study locations across Illinois, Michigan, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.