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NCT02604459 · ClinicalTrials.gov registry record · NA
Does Optimized General Anesthesia Care Reduce Postoperative Delirium?
A NA study, sponsored by University of Missouri-Columbia.
- Terminated
- Registry status
- NA
- Development phase
- 145
- Enrollment target
NCT02604459: Clinical Trial NA study, sponsored by University of Missouri-Columbia.
NCT02604459 is a NA study that was terminated before completion, run by University of Missouri-Columbia. The registered enrollment target is 145 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02604459, a NA study, was terminated before completion, sponsored by University of Missouri-Columbia.
- TERMINATED
- Registry status
- NA
- Development phase
- 145 participants
- Enrollment target
Study Summary
Postoperative delirium occurs in up to 65% of elders undergoing surgery for repair of a hip fracture and this complication is independently associated with increased morbidity, mortality, length of hospital stay, and placement in long-term care institutions. To date, the only intervention shown to be effective at minimizing postoperative delirium is a proactive geriatric consultation. This prospective randomized clinical trial will randomize 160 adults, aged 65 years or older, to either optimized general anesthesia or usual general anesthesia care for hip fracture surgery to determine if the optimized anesthesia management reduces the severity of postoperative delirium.
Primary Outcome
Delirium Rating Scale-Revised-98 (DRS-R-98) is a 16-item clinician-rated scale with 13 severity items and 3 diagnostic items (maximum severity score of 39 points). Higher scores indicate more severe delirium; score of 0 indicates no delirium. Only the number of patients who had high scores on the DRS-R-98 are reported.
Interventions
- DRUG propofol
- PROCEDURE General anesthesia
- DEVICE cerebral oximeter (Fore-Sight)
- DEVICE depth of anesthesia monitor (BIS)
- PROCEDURE BP management
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 145 participants |
| Start Date | 2015-06-01 |
| Est. Completion | 2018-02-28 |
| Phase | NA |
Why NCT02604459 stopped before completion
NCT02604459 is an interventional study that assigns participants to a tested intervention. The registered 145 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 5 interventions - of which propofol is the first listed.
NCT02604459 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02604459 about?
NCT02604459 is a clinical study titled "Does Optimized General Anesthesia Care Reduce Postoperative Delirium?". Postoperative delirium occurs in up to 65% of elders undergoing surgery for repair of a hip fracture and this complication is independently associated with increased morbidity, mortality, length of hospital stay, and placement in long-term care institutions. To date, the only intervention shown to b...
What is the current status of trial NCT02604459?
This trial is currently terminated. It is a NA study. The enrollment target is 145 participants. The study started on 2015-06-01. Estimated completion is 2018-02-28.
What interventions are being tested in trial NCT02604459?
The interventions under investigation include: propofol (DRUG), General anesthesia (PROCEDURE), cerebral oximeter (Fore-Sight) (DEVICE), depth of anesthesia monitor (BIS) (DEVICE), BP management (PROCEDURE).
Who is sponsoring clinical trial NCT02604459?
This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02604459's enrollment target sits among peer trials
145 705th of 2000 higher than 1,295 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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