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NCT02598778 · ClinicalTrials.gov registry record · Phase 2
Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction
A Phase 2 study, sponsored by Montefiore Medical Center.
- Terminated
- Registry status
- Phase 2
- Development phase
- 12
- Enrollment target
NCT02598778: Clinical Trial Phase 2 study, sponsored by Montefiore Medical Center.
NCT02598778 is a Phase 2 study that was terminated before completion, run by Montefiore Medical Center. The registered enrollment target is 12 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02598778, a Phase 2 study, was terminated before completion, sponsored by Montefiore Medical Center.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 12 participants
- Enrollment target
Study Summary
This study compared four mouth rinses/chews for their ability to reduce Streptococcus Mutans after usage. The four that were compared were chlorhexidine gluconate (0.12%), sodium fluoride (0.05%), paraffin wax chewing gum (sugar free), and deionized water. The paraffin wax chewing gum replaced the originally planned coconut oil and served as a placebo comparator.
Primary Outcome
Oral salivary sample obtained and plated on MSB (mitis salivarius-bacitracin) agar petri dish to determine Streptococcus mutans (S. mutans) levels. Values in each row in the Outcome Measure Data Table represent percentage change (increase denoted by positive number, decrease denoted by negative number) in S. mutans colonies from baseline (pre rinse/chew) sample for a single participant within that particular Arm/Group. Row titles have been arbitrarily identified as 'First Participant', 'Second
Interventions
- DRUG Chlorhexidine gluconate (0.12%)
- DRUG Sodium Fluoride (0.05%)
- OTHER Paraffin wax chewing gum (sugar-free)
- OTHER Deionized water
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2015-11-01 |
| Est. Completion | 2016-04-01 |
| Phase | Phase 2 |
Why NCT02598778 stopped before completion
NCT02598778 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 4 interventions - of which Chlorhexidine gluconate (0.12%) is the first listed.
NCT02598778 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02598778 about?
NCT02598778 is a clinical study titled "Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction". This study compared four mouth rinses/chews for their ability to reduce Streptococcus Mutans after usage. The four that were compared were chlorhexidine gluconate (0.12%), sodium fluoride (0.05%), paraffin wax chewing gum (sugar free), and deionized water. The paraffin wax chewing gum replaced the o...
What is the current status of trial NCT02598778?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2015-11-01. Estimated completion is 2016-04-01.
What interventions are being tested in trial NCT02598778?
The interventions under investigation include: Chlorhexidine gluconate (0.12%) (DRUG), Sodium Fluoride (0.05%) (DRUG), Paraffin wax chewing gum (sugar-free) (OTHER), Deionized water (OTHER).
Who is sponsoring clinical trial NCT02598778?
This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02598778's enrollment target sits among peer trials
12 1948th of 2000 higher than 34 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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