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NCT02577497 · ClinicalTrials.gov registry record · Phase 4
Effect of Extra- Fine Versus Coarse-Particle Inhaled Corticosteroids (ICS) on Ventilation Heterogeneity in Children With Poorly Controlled Asthma
A Phase 4 study of Asthma, sponsored by University of Virginia.
- Completed
- Registry status
- Phase 4
- Development phase
- 31
- Enrollment target
- 1
- Study location
NCT02577497: Completed Phase 4 study of Asthma, sponsored by University of Virginia.
NCT02577497 is a Phase 4 study of Asthma that has completed, run by University of Virginia. The registered enrollment target is 31 participants, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02577497, a Phase 4 study of Asthma, has completed, sponsored by University of Virginia.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 31 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective of the study is to show that ventilation heterogeneity identified by hyperpolarized helium-3 lung MRI is prevalent children with poorly controlled asthma despite guidelines-based treatment with ICS. The secondary objective is to demonstrate whether or not eight weeks of treatment with extra-fine particle ICS (HFA-BDP) improves ventilation heterogeneity compared to treatment with a coarse particle ICS (fluticasone HFA or dry powder).
Primary Outcome
VHI = lung defect volume divided by total lung volume. It is a ratio scale.
Conditions Studied
Interventions
- DRUG beclomethasone
- DRUG fluticasone
Study Locations (1)
Virginia
- University of Virginia - Fontaine Research Park - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2016-06 |
| Est. Completion | 2018-07-06 |
| Phase | Phase 4 |
What the finished NCT02577497 record still lists
NCT02577497 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Asthma appearing as the primary indexed condition, and to 2 interventions - of which beclomethasone is the first listed.
NCT02577497 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT02577497 about?
NCT02577497 is a clinical study titled "Effect of Extra- Fine Versus Coarse-Particle Inhaled Corticosteroids (ICS) on Ventilation Heterogeneity in Children With Poorly Controlled Asthma". The primary objective of the study is to show that ventilation heterogeneity identified by hyperpolarized helium-3 lung MRI is prevalent children with poorly controlled asthma despite guidelines-based treatment with ICS. The secondary objective is to demonstrate whether or not eight weeks of treatme...
What is the current status of trial NCT02577497?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 31 participants. The study started on 2016-06. Estimated completion is 2018-07-06.
What conditions does trial NCT02577497 study?
This clinical trial studies the following conditions: Asthma.
What interventions are being tested in trial NCT02577497?
The interventions under investigation include: beclomethasone (DRUG), fluticasone (DRUG).
Who is sponsoring clinical trial NCT02577497?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02577497 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Asthma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02577497's enrollment target sits among peer trials
31 301st of 374 higher than 71 of 374 other Asthma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Asthma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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