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NCT02559310 · ClinicalTrials.gov registry record · Phase 3
Study to Compare Lefamulin to Moxifloxacin (With or Without Linezolid) for the Treatment of Adults With Pneumonia
A Phase 3 study, sponsored by Nabriva Therapeutics.
- Completed
- Registry status
- Phase 3
- Development phase
- 551
- Enrollment target
NCT02559310: Completed Phase 3 study, sponsored by Nabriva Therapeutics.
NCT02559310 is a Phase 3 study that has completed, run by Nabriva Therapeutics. The registered enrollment target is 551 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (29% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02559310, a Phase 3 study, has completed, sponsored by Nabriva Therapeutics.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 551 participants
- Enrollment target
Study Summary
This study evaluates the safety and efficacy of lefamulin, a pleuromutilin, for the treatment of adults with moderate to severe community-acquired bacterial pneumonia.
Primary Outcome
ECR was defined as survival with improvement in at least 2 signs and symptoms of CABP (relative to baseline), no worsening of any CABP sign or symptom, and no use of concomitant antibiotics (other than adjunctive linezolid, as allowed by the study protocol) for the treatment of CABP through the ECR assessment.
Interventions
- DRUG Moxifloxacin
- DRUG Linezolid
- DRUG lefamulin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 551 participants |
| Start Date | 2015-09 |
| Est. Completion | 2017-05 |
| Phase | Phase 3 |
What the finished NCT02559310 record still lists
NCT02559310 is an interventional study that assigns participants to a tested intervention. The registered 551 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (29% lower).
The record links to 0 conditions, and to 3 interventions - of which Moxifloxacin is the first listed.
NCT02559310 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02559310 about?
NCT02559310 is a clinical study titled "Study to Compare Lefamulin to Moxifloxacin (With or Without Linezolid) for the Treatment of Adults With Pneumonia". This study evaluates the safety and efficacy of lefamulin, a pleuromutilin, for the treatment of adults with moderate to severe community-acquired bacterial pneumonia.
What is the current status of trial NCT02559310?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 551 participants. The study started on 2015-09. Estimated completion is 2017-05.
What interventions are being tested in trial NCT02559310?
The interventions under investigation include: Moxifloxacin (DRUG), Linezolid (DRUG), lefamulin (DRUG).
Who is sponsoring clinical trial NCT02559310?
This trial is sponsored by Nabriva Therapeutics, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02559310's enrollment target sits among peer trials
551 680th of 2000 higher than 1,321 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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