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NCT02556372 · ClinicalTrials.gov registry record · Phase 2

Liver Test Study of Using JKB-122 in Autoimmune Hepatitis (AIH) Patients Who Are Refractory or Intolerant to Current Therapies

A Phase 2 study of Autoimmune Hepatitis, sponsored by TaiwanJ Pharmaceuticals Co..

Completed
Registry status
Phase 2
Development phase
20
Enrollment target
16
Study locations

NCT02556372 is a Phase 2 study of Autoimmune Hepatitis that has completed, run by TaiwanJ Pharmaceuticals Co.. The registered enrollment target is 20 participants, below the 224-participant average among 5 other Autoimmune Hepatitis trials with a reported enrollment target (91% lower). The trial reports 16 study locations across 10 states.

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The verdict

NCT02556372, a Phase 2 study of Autoimmune Hepatitis, has completed, sponsored by TaiwanJ Pharmaceuticals Co..

COMPLETED
Registry status
Phase 2
Development phase
20 participants
Enrollment target
16
Study locations

Study Summary

This is a Phase 2, pilot study in which JKB-122 is given once daily for 24 weeks in subjects with autoimmune hepatitis (AIH) who have liver enzymes that are 1.25 to 10 times the upper limit of normal (ULN) and who have had a failed response to, incomplete response to, intolerant to, ineligible to, or unwilling to take current immunosuppressant therapies. The dose of JKB-122 will be escalated monthly.

Conditions Studied

Interventions

  • DRUG JKB-122

Study Locations (16)

Texas

  • Methodist Dallas Medical Center - Dallas
  • Advanced Liver Therapies, Baylor College of Medicine - Houston
  • The Texas Liver Institute - San Antonio
  • Taxes Liver Institute - San Antonio

California

  • Ruane Clinical Research Group, Inc. - Los Angeles
  • University of California Davis Medical Center - Ticon 1 - Sacramento
  • California Pacific Medical Center - San Francisco

Washington

  • Swedish Medical Center - Organ Transplant and Liver Center - Seattle
  • University of Washington - Seattle

Florida

  • University of Florida Hepatology Research at CTRB - Gainesville

Illinois

  • Northwestern University - Chicago

Indiana

  • Indiana University School of Medicine - Indianapolis

Louisiana

  • Tulane University - New Orleans

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2016-04-30
Est. Completion 2019-01-21
Phase Phase 2

Sponsor

TaiwanJ Pharmaceuticals Co.

1 total trials

What the Registry Record Tells You About NCT02556372

The ClinicalTrials.gov registry entry for NCT02556372 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 224-participant average among 5 other Autoimmune Hepatitis trials with a reported enrollment target (91% lower). The listed sponsor is TaiwanJ Pharmaceuticals Co., which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Autoimmune Hepatitis appearing as the primary indexed condition, and to 1 intervention - of which JKB-122 is the first listed.

NCT02556372 reports 16 study locations spanning 10 distinct geographic areas - top geographies include Texas, California, Washington.

Frequently Asked Questions

What is clinical trial NCT02556372 about?

NCT02556372 is a clinical study titled "Liver Test Study of Using JKB-122 in Autoimmune Hepatitis (AIH) Patients Who Are Refractory or Intolerant to Current Therapies". This is a Phase 2, pilot study in which JKB-122 is given once daily for 24 weeks in subjects with autoimmune hepatitis (AIH) who have liver enzymes that are 1.25 to 10 times the upper limit of normal (ULN) and who have had a failed response to, incomplete response to, intolerant to, ineligible to, o...

What is the current status of trial NCT02556372?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2016-04-30. Estimated completion is 2019-01-21.

What conditions does trial NCT02556372 study?

This clinical trial studies the following conditions: Autoimmune Hepatitis.

What interventions are being tested in trial NCT02556372?

The interventions under investigation include: JKB-122 (DRUG).

Who is sponsoring clinical trial NCT02556372?

This trial is sponsored by TaiwanJ Pharmaceuticals Co., which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02556372 being conducted?

This trial has 16 study locations across California, Florida, Illinois, Indiana, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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