Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02554396 · ClinicalTrials.gov registry record · Phase 2

Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia

A Phase 2 study of Presbyopia, sponsored by LENZ Therapeutics.

Completed
Registry status
Phase 2
Development phase
20
Enrollment target
1
Study location

NCT02554396 is a Phase 2 study of Presbyopia that has completed, run by LENZ Therapeutics. The registered enrollment target is 20 participants, below the 270-participant average among 38 other Presbyopia trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02554396, a Phase 2 study of Presbyopia, has completed, sponsored by LENZ Therapeutics.

COMPLETED
Registry status
Phase 2
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

This is a one-day, randomized, double-masked, single-center evaluation of the efficacy and safety of PRX-100 ophthalmic solution compared to placebo in 20 subjects (randomized 4:1, PRX-100:placebo) to evaluate the safety of PRX-100 and the magnitude and duration of effects on improving near-vision acuity.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG PRX-100

Study Locations (1)

Massachusetts

  • Andover Eye Associates - Andover

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2015-09
Est. Completion 2015-11
Phase Phase 2

Sponsor

LENZ Therapeutics

8 total trials

What the Registry Record Tells You About NCT02554396

The ClinicalTrials.gov registry entry for NCT02554396 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 270-participant average among 38 other Presbyopia trials with a reported enrollment target (93% lower). The listed sponsor is LENZ Therapeutics, which has 8 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Presbyopia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02554396 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT02554396 about?

NCT02554396 is a clinical study titled "Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia". This is a one-day, randomized, double-masked, single-center evaluation of the efficacy and safety of PRX-100 ophthalmic solution compared to placebo in 20 subjects (randomized 4:1, PRX-100:placebo) to evaluate the safety of PRX-100 and the magnitude and duration of effects on improving near-vision a...

What is the current status of trial NCT02554396?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2015-09. Estimated completion is 2015-11.

What conditions does trial NCT02554396 study?

This clinical trial studies the following conditions: Presbyopia.

What interventions are being tested in trial NCT02554396?

The interventions under investigation include: Placebo (DRUG), PRX-100 (DRUG).

Who is sponsoring clinical trial NCT02554396?

This trial is sponsored by LENZ Therapeutics, which has 8 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02554396 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Presbyopia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.