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NCT02553447 · ClinicalTrials.gov registry record · NA
Cholecalciferol in Newly Diagnosed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia With Vitamin D Deficiency
A NA study, sponsored by University of Nebraska.
- Completed
- Registry status
- NA
- Development phase
- 197
- Enrollment target
NCT02553447: Completed NA study, sponsored by University of Nebraska.
NCT02553447 is a NA study that has completed, run by University of Nebraska. The registered enrollment target is 197 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02553447, a NA study, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- NA
- Development phase
- 197 participants
- Enrollment target
Study Summary
This randomized pilot early phase I trial studies how well cholecalciferol works in treating patients with newly diagnosed non-Hodgkin lymphoma or chronic lymphocytic leukemia with low levels of vitamin D (vitamin D deficiency). Cholecalciferol may increase levels of vitamin D and improve survival in patients with non-Hodgkin lymphoma or chronic lymphocytic leukemia receiving standard of care chemotherapy.
Primary Outcome
The 3-year progression-free survival will be presented using Kaplan-Meier curves and will be presented for the normal serum vitamin D control group and the low and high dose randomized groups. Each randomized group (low and high dose) will be compared to a historical fixed expected 3-year progression-free survival of 45% using a one-sample logrank test following the method of Woolson (1981). Progression was determined by Investigator assessment based on clinical evidence of disease relapse, prog
Interventions
- DIETARY_SUPPLEMENT Cholecalciferol
- OTHER Laboratory Biomarker Analysis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 197 participants |
| Start Date | 2015-10-19 |
| Est. Completion | 2025-04-12 |
| Phase | NA |
What the finished NCT02553447 record still lists
NCT02553447 is an interventional study that assigns participants to a tested intervention. The registered 197 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 2 interventions - of which Cholecalciferol is the first listed.
NCT02553447 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02553447 about?
NCT02553447 is a clinical study titled "Cholecalciferol in Newly Diagnosed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia With Vitamin D Deficiency". This randomized pilot early phase I trial studies how well cholecalciferol works in treating patients with newly diagnosed non-Hodgkin lymphoma or chronic lymphocytic leukemia with low levels of vitamin D (vitamin D deficiency). Cholecalciferol may increase levels of vitamin D and improve survival i...
What is the current status of trial NCT02553447?
This trial is currently completed. It is a NA study. The enrollment target is 197 participants. The study started on 2015-10-19. Estimated completion is 2025-04-12.
What interventions are being tested in trial NCT02553447?
The interventions under investigation include: Cholecalciferol (DIETARY_SUPPLEMENT), Laboratory Biomarker Analysis (OTHER).
Who is sponsoring clinical trial NCT02553447?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02553447's enrollment target sits among peer trials
197 567th of 2000 higher than 1,434 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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