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NCT02545868 · ClinicalTrials.gov registry record · Phase 3

A Study to Evaluate the Effects of Ocrelizumab on Immune Responses In Participants With Relapsing Forms of Multiple Sclerosis

A Phase 3 study, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 3
Development phase
102
Enrollment target

NCT02545868 is a Phase 3 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 102 participants.

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The verdict

NCT02545868, a Phase 3 study, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 3
Development phase
102 participants
Enrollment target

Study Summary

This multicenter, randomized, open-label study will evaluate the immune response to vaccines (tetanus toxoid \[TT\]-containing adsorbed vaccine, 23-valent pneumococcal polysaccharide vaccine \[23-PPV\] either unboosted or boosted with 13-valent pneumococcal conjugate vaccine \[13-PCV\], influenza vaccine, keyhole limpet hemocyanin \[KLH\]) after administration of a dose of ocrelizumab (OCR) in participants with relapsing multiple sclerosis (RMS).

Interventions

  • BIOLOGICAL Influenza Vaccine
  • BIOLOGICAL KLH
  • BIOLOGICAL 23-PPV
  • BIOLOGICAL 13-PCV Booster
  • DRUG OCR

Trial Details

FieldValue
Enrollment Target 102 participants
Start Date 2015-10-27
Est. Completion 2021-09-21
Phase Phase 3

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT02545868

The ClinicalTrials.gov registry entry for NCT02545868 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 102 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Influenza Vaccine is the first listed.

NCT02545868 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02545868 about?

NCT02545868 is a clinical study titled "A Study to Evaluate the Effects of Ocrelizumab on Immune Responses In Participants With Relapsing Forms of Multiple Sclerosis". This multicenter, randomized, open-label study will evaluate the immune response to vaccines (tetanus toxoid \[TT\]-containing adsorbed vaccine, 23-valent pneumococcal polysaccharide vaccine \[23-PPV\] either unboosted or boosted with 13-valent pneumococcal conjugate vaccine \[13-PCV\], influenza va...

What is the current status of trial NCT02545868?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 102 participants. The study started on 2015-10-27. Estimated completion is 2021-09-21.

What interventions are being tested in trial NCT02545868?

The interventions under investigation include: Influenza Vaccine (BIOLOGICAL), KLH (BIOLOGICAL), 23-PPV (BIOLOGICAL), 13-PCV Booster (BIOLOGICAL), OCR (DRUG).

Who is sponsoring clinical trial NCT02545868?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.