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NCT02535325 · ClinicalTrials.gov registry record · Phase 1

Methoxyamine Hydrochloride, Pemetrexed Disodium, Cisplatin, and Radiation Therapy in Treating Patients With Stage IIIA-IV Non-small Cell Lung Cancer

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
17
Enrollment target

NCT02535325: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT02535325 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 17 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02535325, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
17 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and best dose of methoxyamine when given together with pemetrexed disodium, cisplatin, and radiation therapy in treating patients with stage IIIA-IV non-small cell lung cancer. Drugs used in chemotherapy, such as methoxyamine hydrochloride, pemetrexed disodium, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells and shrink tumors. Giving methoxyamine hydrochloride together with pemetrexed disodium, cisplatin, and radiation therapy may kill more tumor cells.

Interventions

  • DRUG Cisplatin
  • RADIATION Intensity-Modulated Radiation Therapy
  • RADIATION 3-Dimensional Conformal Radiation Therapy
  • DRUG Methoxyamine
  • DRUG Methoxyamine Hydrochloride

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2015-09-30
Est. Completion 2022-06-14
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT02535325

The ClinicalTrials.gov registry entry for NCT02535325 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Cisplatin is the first listed.

NCT02535325 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02535325 about?

NCT02535325 is a clinical study titled "Methoxyamine Hydrochloride, Pemetrexed Disodium, Cisplatin, and Radiation Therapy in Treating Patients With Stage IIIA-IV Non-small Cell Lung Cancer". This phase I trial studies the side effects and best dose of methoxyamine when given together with pemetrexed disodium, cisplatin, and radiation therapy in treating patients with stage IIIA-IV non-small cell lung cancer. Drugs used in chemotherapy, such as methoxyamine hydrochloride, pemetrexed diso...

What is the current status of trial NCT02535325?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2015-09-30. Estimated completion is 2022-06-14.

What interventions are being tested in trial NCT02535325?

The interventions under investigation include: Cisplatin (DRUG), Intensity-Modulated Radiation Therapy (RADIATION), 3-Dimensional Conformal Radiation Therapy (RADIATION), Methoxyamine (DRUG), Methoxyamine Hydrochloride (DRUG).

Who is sponsoring clinical trial NCT02535325?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.