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NCT02520778 · ClinicalTrials.gov registry record · Phase 1

Osimertinib and Navitoclax in Treating Patients With EGFR-Positive Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
27
Enrollment target

NCT02520778: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT02520778 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 27 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02520778, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
27 participants
Enrollment target

Study Summary

This phase Ib trial studies the side effects and best dose of osimertinib and navitoclax when given together and to see how well they work in treating patients with previously treated epidermal growth factor receptor (EGFR)-positive non-small cell lung cancer that has spread to other places in the body (metastatic) or has not responded to previous treatment with initial EGFR kinase inhibitor. Osimertinib and navitoclax may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Interventions

  • DRUG Osimertinib
  • DRUG Navitoclax

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2016-08-30
Est. Completion 2023-12-04
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT02520778

The ClinicalTrials.gov registry entry for NCT02520778 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Osimertinib is the first listed.

NCT02520778 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02520778 about?

NCT02520778 is a clinical study titled "Osimertinib and Navitoclax in Treating Patients With EGFR-Positive Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer". This phase Ib trial studies the side effects and best dose of osimertinib and navitoclax when given together and to see how well they work in treating patients with previously treated epidermal growth factor receptor (EGFR)-positive non-small cell lung cancer that has spread to other places in the b...

What is the current status of trial NCT02520778?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2016-08-30. Estimated completion is 2023-12-04.

What interventions are being tested in trial NCT02520778?

The interventions under investigation include: Osimertinib (DRUG), Navitoclax (DRUG).

Who is sponsoring clinical trial NCT02520778?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.