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NCT02505594 · ClinicalTrials.gov registry record
Potential Mechanism of Exercise Impairment in OSA
A clinical trial, sponsored by University of California, San Diego.
- Completed
- Registry status
- 29
- Enrollment target
NCT02505594: Completed study, sponsored by University of California, San Diego.
NCT02505594 is a clinical trial that has completed, run by University of California, San Diego. The registered enrollment target is 29 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02505594 has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- 29 participants
- Enrollment target
Study Summary
Obstructive sleep apnea (OSA) is a common disorder with major cardiovascular sequelae. A recent study confirmed that OSA is associated with impaired exercise capacity and increasing OSA severity predicts worsening exercise capacity, which is a marker of potential increased cardiovascular risk. However, potential mechanisms of decreased exercise capacity caused by OSA remain unclear. Several pathophysiologic mechanisms of OSA have been proposed and investigators hypothesize that endothelial dysfunction leading to exercise-induced right ventricular dysfunction and associated pulmonary hypertension is the potential mechanism for impaired exercise capacity in OSA.
Primary Outcome
EndoPAT is a non-invasive measurement of endothelial function, using peripheral arterial tonometry. Exercise tolerance is measured by Cardiopulmonary exercise testing (CPET). Effects of OSA on exercise tolerance and endothelial function will be evaluated.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2015-07 |
| Est. Completion | 2017-05-09 |
What the finished NCT02505594 record still lists
NCT02505594 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 29 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02505594 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02505594 about?
NCT02505594 is a clinical study titled "Potential Mechanism of Exercise Impairment in OSA". Obstructive sleep apnea (OSA) is a common disorder with major cardiovascular sequelae. A recent study confirmed that OSA is associated with impaired exercise capacity and increasing OSA severity predicts worsening exercise capacity, which is a marker of potential increased cardiovascular risk. Howev...
What is the current status of trial NCT02505594?
This trial is currently completed. The enrollment target is 29 participants. The study started on 2015-07. Estimated completion is 2017-05-09.
Who is sponsoring clinical trial NCT02505594?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
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