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NCT02504840 · ClinicalTrials.gov registry record
Natural History of Multiple Sclerosis and Its Mimickers
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 104
- Enrollment target
NCT02504840: Completed study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT02504840 is a clinical trial that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 104 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02504840 has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 104 participants
- Enrollment target
Study Summary
Background: \- Magnetic resonance imaging (MRI) has been used for decades to help diagnose and monitor neurological disorders like multiple sclerosis (MS). Researchers want to improve how MRI pictures are taken. They also want to learn more about using newer MRIs with stronger magnets to get better pictures than standard MRIs provide. Objectives: \- To collect data that will help researchers better understand MS and related diseases. Eligibility: * Adults 18 and older with MS or MRI findings that appear similar to MS, or with other neurological diseases that may look or act like MS. * Healthy adult volunteers. Design: * Participants will be screened with a review of their medical records. * Participants will have a baseline visit. It will include a physical exam, medical history, and neurological exam. They may have blood tests. * The study will last indefinitely. * Participants may have MRIs. Some MRIs may include a contrast dye. For this, a needle will be used to guide a thin plastic tube into an arm vein. * Participants may have up to 2 lumbar punctures per year. Skin will be numbed and a needle inserted between back bones will remove fluid. * Participants may give saliva samples and have an eye exam. * Participants may have evoked potential tests. These measure how the nervous system responds to different types of stimulation. Participants may sit in front of a TV and watch pictures on the screen. Or they may wear earphones that make a clicking noise or static. Or they may get a small electrical shock that may tingle and cause a hand or foot twitch. * Participants may have tests of strength, spasticity, sensations, balance, and/or walking.
Primary Outcome
Imaging measures will focus on features related to the central nervous system (CNS), particularly focal lesions. Clinical measures will include standard and established MS disability scales as well as quantitative measures related to function. Biological measures will include genotype, gene expression, proteomics, virological studies, and immunological profiling.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 104 participants |
| Start Date | 2015-07-23 |
| Est. Completion | 2020-03-05 |
What the finished NCT02504840 record still lists
NCT02504840 is an observational study that tracks outcomes without assigning an intervention. The registered 104 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT02504840 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02504840 about?
NCT02504840 is a clinical study titled "Natural History of Multiple Sclerosis and Its Mimickers". Background: \- Magnetic resonance imaging (MRI) has been used for decades to help diagnose and monitor neurological disorders like multiple sclerosis (MS). Researchers want to improve how MRI pictures are taken. They also want to learn more about using newer MRIs with stronger magnets to get better...
What is the current status of trial NCT02504840?
This trial is currently completed. The enrollment target is 104 participants. The study started on 2015-07-23. Estimated completion is 2020-03-05.
Who is sponsoring clinical trial NCT02504840?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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