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NCT02482311 · ClinicalTrials.gov registry record · Phase 1
Safety, Tolerance, PK, and Anti-tumour Activity of AZD1775 Monotherapy in Patients With Advanced Solid Tumours
A Phase 1 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 1
- Development phase
- 92
- Enrollment target
NCT02482311: Completed Phase 1 study, sponsored by AstraZeneca.
NCT02482311 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 92 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02482311, a Phase 1 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 92 participants
- Enrollment target
Study Summary
This is an open-label, multi-centre, Phase Ib study of AZD1775 designed to assess the safety, tolerability, pharmacokinetics, and anti-tumour activity of AZD1775 monotherapy in patients with advanced solid tumours.
Primary Outcome
The AZD1775 dose is considered safe and tolerable if ≤ 1 of 6 patients experiences a DLT.
Interventions
- DRUG AZD 1775
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 92 participants |
| Start Date | 2015-07-01 |
| Est. Completion | 2019-08-22 |
| Phase | Phase 1 |
What the finished NCT02482311 record still lists
NCT02482311 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 92 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% higher).
The record links to 0 conditions, and to 1 intervention - of which AZD 1775 is the first listed.
NCT02482311 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02482311 about?
NCT02482311 is a clinical study titled "Safety, Tolerance, PK, and Anti-tumour Activity of AZD1775 Monotherapy in Patients With Advanced Solid Tumours". This is an open-label, multi-centre, Phase Ib study of AZD1775 designed to assess the safety, tolerability, pharmacokinetics, and anti-tumour activity of AZD1775 monotherapy in patients with advanced solid tumours.
What is the current status of trial NCT02482311?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 92 participants. The study started on 2015-07-01. Estimated completion is 2019-08-22.
What interventions are being tested in trial NCT02482311?
The interventions under investigation include: AZD 1775 (DRUG).
Who is sponsoring clinical trial NCT02482311?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02482311's enrollment target sits among peer trials
92 625th of 2000 higher than 1,375 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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