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NCT02481869 · ClinicalTrials.gov registry record · NA

Platelet Rich Plasma Injection in Pilon Fractures

A NA study, sponsored by University of Missouri-Columbia.

Completed
Registry status
NA
Development phase
11
Enrollment target

NCT02481869: Completed NA study, sponsored by University of Missouri-Columbia.

NCT02481869 is a NA study that has completed, run by University of Missouri-Columbia. The registered enrollment target is 11 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02481869, a NA study, has completed, sponsored by University of Missouri-Columbia.

COMPLETED
Registry status
NA
Development phase
11 participants
Enrollment target

Study Summary

Patients who sustain broken ankles have a very high risk of developing arthritis soon after injury (within 2 years). This arthritis can cause increased pain and a decrease level of function, especially if the injury occurs at an early age. During and shortly after ankle injury, there is an inflammatory chemical process that takes place in the ankle that can cause damage to the cartilage in the ankle joint. The investigators want to use what is called Platelet Rich Plasma (PRP), which is produced from a small amount of the patient's own blood, to inject into the injured ankle to see if they can decrease the inflammation that happens after the injury and to see if they can decrease arthritis.

Primary Outcome

Inflammatory Biomarkers will be measured (pg/ml) at the time of definitive Fixation

Interventions

  • BIOLOGICAL Arthrocentesis/PRP
  • DRUG Arthrocentesis/Saline

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2015-06
Est. Completion 2019-11
Phase NA
University of Missouri-Columbia

291 total trials

What the finished NCT02481869 record still lists

NCT02481869 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Arthrocentesis/PRP is the first listed.

NCT02481869 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02481869 about?

NCT02481869 is a clinical study titled "Platelet Rich Plasma Injection in Pilon Fractures". Patients who sustain broken ankles have a very high risk of developing arthritis soon after injury (within 2 years). This arthritis can cause increased pain and a decrease level of function, especially if the injury occurs at an early age. During and shortly after ankle injury, there is an inflammat...

What is the current status of trial NCT02481869?

This trial is currently completed. It is a NA study. The enrollment target is 11 participants. The study started on 2015-06. Estimated completion is 2019-11.

What interventions are being tested in trial NCT02481869?

The interventions under investigation include: Arthrocentesis/PRP (BIOLOGICAL), Arthrocentesis/Saline (DRUG).

Who is sponsoring clinical trial NCT02481869?

This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02481869's enrollment target sits among peer trials

11 1927th of 2000 higher than 74 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02481869, the US trial registry maintained by the National Library of Medicine. NCT02481869 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.