Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02469428 · ClinicalTrials.gov registry record · NA
Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers
A NA study, sponsored by Environmental Protection Agency (EPA).
- Completed
- Registry status
- NA
- Development phase
- 14
- Enrollment target
NCT02469428: Completed NA study, sponsored by Environmental Protection Agency (EPA).
NCT02469428 is a NA study that has completed, run by Environmental Protection Agency (EPA). The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02469428, a NA study, has completed, sponsored by Environmental Protection Agency (EPA).
- COMPLETED
- Registry status
- NA
- Development phase
- 14 participants
- Enrollment target
Study Summary
The purpose of this protocol is to assess whether epigenetic factors in healthy individuals make a person more or less responsive to lung inflammation following ozone exposures.
Primary Outcome
18 hrs following exposures the subjects will undergo a research bronchoscopy where lavage fluid and epithelial cells via brush biopsy will be collected. Protein content will be assessed in lavage fluid. Changes in inflammatory genes will be measured in epithelial cells. DNA will be extracted from epithelial cells and DNA methylation arrays will be run.
Interventions
- OTHER Ozone
- OTHER Clean air
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2013-12 |
| Est. Completion | 2018-11-05 |
| Phase | NA |
What the finished NCT02469428 record still lists
NCT02469428 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Ozone is the first listed.
NCT02469428 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02469428 about?
NCT02469428 is a clinical study titled "Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers". The purpose of this protocol is to assess whether epigenetic factors in healthy individuals make a person more or less responsive to lung inflammation following ozone exposures.
What is the current status of trial NCT02469428?
This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2013-12. Estimated completion is 2018-11-05.
What interventions are being tested in trial NCT02469428?
The interventions under investigation include: Ozone (OTHER), Clean air (OTHER).
Who is sponsoring clinical trial NCT02469428?
This trial is sponsored by Environmental Protection Agency (EPA), which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02469428's enrollment target sits among peer trials
14 1909th of 2000 higher than 90 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02523092 · 14 participants · Phase 4
Use of CXCL9 as a Biomarker of Acthar Efficacy
- NCT04263285 · 14 participants · NA
Treatment of Depression Post-SCI
- NCT04743271 · 14 participants · NA
Food and Circadian Timing
- NCT05065671 · 14 participants · Phase 1
Microbiome Derived Metabolism and Pharmacokinetics
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia