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NCT02469246 · ClinicalTrials.gov registry record · Phase 3
Switch Study to Evaluate F/TAF in HIV-1 Infected Adults Who Are Virologically Suppressed on Regimens Containing ABC/3TC
A Phase 3 study, sponsored by Gilead Sciences.
- Completed
- Registry status
- Phase 3
- Development phase
- 567
- Enrollment target
NCT02469246: Completed Phase 3 study, sponsored by Gilead Sciences.
NCT02469246 is a Phase 3 study that has completed, run by Gilead Sciences. The registered enrollment target is 567 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (27% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02469246, a Phase 3 study, has completed, sponsored by Gilead Sciences.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 567 participants
- Enrollment target
Study Summary
The primary objectives of this study are to evaluate the efficacy, safety, and tolerability of switching abacavir/lamivudine (ABC/3TC) fixed-dose combination (FDC) tablets to emtricitabine/tenofovir alafenamide (F/TAF) FDC tablets versus maintaining ABC/3TC in human immunodeficiency virus type 1 (HIV-1) infected adults who are virologically suppressed on regimens containing ABC/3TC.
Primary Outcome
The percentage of participants achieving HIV-1 RNA \< 50 copies/mL at Week 48 was analyzed using the snapshot algorithm, which defines a participant's virologic response status using only the viral load at the predefined time point within an allowed window of time, along with study drug discontinuation status.
Interventions
- DRUG F/TAF
- DRUG F/TAF Placebo
- DRUG ABC/3TC
- DRUG ABC/3TC Placebo
- DRUG 3rd ARV agent
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 567 participants |
| Start Date | 2015-06-29 |
| Est. Completion | 2019-03-13 |
| Phase | Phase 3 |
What the finished NCT02469246 record still lists
NCT02469246 is an interventional study that assigns participants to a tested intervention. The registered 567 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (27% lower).
The record links to 0 conditions, and to 5 interventions - of which F/TAF is the first listed.
NCT02469246 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02469246 about?
NCT02469246 is a clinical study titled "Switch Study to Evaluate F/TAF in HIV-1 Infected Adults Who Are Virologically Suppressed on Regimens Containing ABC/3TC". The primary objectives of this study are to evaluate the efficacy, safety, and tolerability of switching abacavir/lamivudine (ABC/3TC) fixed-dose combination (FDC) tablets to emtricitabine/tenofovir alafenamide (F/TAF) FDC tablets versus maintaining ABC/3TC in human immunodeficiency virus type 1 (HI...
What is the current status of trial NCT02469246?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 567 participants. The study started on 2015-06-29. Estimated completion is 2019-03-13.
What interventions are being tested in trial NCT02469246?
The interventions under investigation include: F/TAF (DRUG), F/TAF Placebo (DRUG), ABC/3TC (DRUG), ABC/3TC Placebo (DRUG), 3rd ARV agent (DRUG).
Who is sponsoring clinical trial NCT02469246?
This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02469246's enrollment target sits among peer trials
567 667th of 2000 higher than 1,334 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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