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NCT02448446 · ClinicalTrials.gov registry record · Phase 1
The Effect of Intravitreal Ranibizumab on Visual Acuity and Hard Exudate Resolution in the Treatment of Diabetic Macular Edema With Center Involved Edema and Lipid Exudates
A Phase 1 study of Diabetic Macular Edema and Hard Lipid Exudates, sponsored by South Coast Retina Center; Carson, McBeath, Boswell.
- Completed
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
- 4
- Study locations
NCT02448446: Completed Phase 1 study of Diabetic Macular Edema and Hard Lipid Exudates, sponsored by South Coast Retina Center; Carson, McBeath, Boswell.
NCT02448446 is a Phase 1 study of Diabetic Macular Edema and Hard Lipid Exudates that has completed, run by South Coast Retina Center; Carson, McBeath, Boswell. The registered enrollment target is 25 participants, below the 3,794-participant average among 63 other Diabetic Macular Edema trials with a reported enrollment target (99% lower). The trial reports 4 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02448446, a Phase 1 study of Diabetic Macular Edema and Hard Lipid Exudates, has completed, sponsored by South Coast Retina Center; Carson, McBeath, Boswell.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
- 4
- Study locations
Study Summary
This is an open-label, Phase I/II study of intravitreally administered 0.3mg ranibizumab in subjects with diabetic macular edema and lipid exudates in the central subfield.
Primary Outcome
Compare Group 1 and Group 2 for best correct visual acuity (BCVA), as assessed by the number of letters read correctly on the ETDRS eye chart at a starting test distance of 4 meters.
Conditions Studied
Interventions
- DRUG ranibizumab 0.3mg
Study Locations (4)
California
- South Coast Retina Center; Carson, McBeath, Boswell, Inc - Huntington Beach
- South Coast Retina Center; Carson, McBeath, and Boswell, Inc - Long Beach
- Retina Partners - Santa Monica
- South Coast Retina Center; Carson, McBeath, Boswell, Inc - Torrance
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2015-08 |
| Est. Completion | 2018-05 |
| Phase | Phase 1 |
What the finished NCT02448446 record still lists
NCT02448446 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 3,794-participant average among 63 other Diabetic Macular Edema trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Diabetic Macular Edema appearing as the primary indexed condition, and to 1 intervention - of which ranibizumab 0.3mg is the first listed.
NCT02448446 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT02448446 about?
NCT02448446 is a clinical study titled "The Effect of Intravitreal Ranibizumab on Visual Acuity and Hard Exudate Resolution in the Treatment of Diabetic Macular Edema With Center Involved Edema and Lipid Exudates". This is an open-label, Phase I/II study of intravitreally administered 0.3mg ranibizumab in subjects with diabetic macular edema and lipid exudates in the central subfield.
What is the current status of trial NCT02448446?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2015-08. Estimated completion is 2018-05.
What conditions does trial NCT02448446 study?
This clinical trial studies the following conditions: Diabetic Macular Edema, Hard Lipid Exudates.
What interventions are being tested in trial NCT02448446?
The interventions under investigation include: ranibizumab 0.3mg (DRUG).
Who is sponsoring clinical trial NCT02448446?
This trial is sponsored by South Coast Retina Center; Carson, McBeath, Boswell, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02448446 being conducted?
This trial has 4 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Diabetic Macular Edema
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02448446's enrollment target sits among peer trials
25 49th of 63 higher than 14 of 63 other Diabetic Macular Edema trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diabetic Macular Edema trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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