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NCT02437318 · ClinicalTrials.gov registry record · Phase 3

Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant in Men and Postmenopausal Women With Advanced Breast Cancer Which Progressed on or After Aromatase Inhibitor Treatment.

A Phase 3 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
572
Enrollment target

NCT02437318 is a Phase 3 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 572 participants.

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The verdict

NCT02437318, a Phase 3 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
572 participants
Enrollment target

Study Summary

To determine whether treatment with alpelisib plus fulvestrant prolonged progression-free survival (PFS) compared to fulvestrant and placebo in men and postmenopausal women with hormone receptor positive (HR+), human epidermal growth factor receptor-2 (HER2)-negative advanced breast cancer, who received prior treatment with an aromatase Inhibitor (AI) either as (neo)adjuvant or for advanced disease.

Interventions

  • DRUG Placebo
  • DRUG Fulvestrant
  • DRUG Alpelisib

Trial Details

FieldValue
Enrollment Target 572 participants
Start Date 2015-07-23
Est. Completion 2023-06-09
Phase Phase 3

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT02437318

The ClinicalTrials.gov registry entry for NCT02437318 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 572 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02437318 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02437318 about?

NCT02437318 is a clinical study titled "Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant in Men and Postmenopausal Women With Advanced Breast Cancer Which Progressed on or After Aromatase Inhibitor Treatment.". To determine whether treatment with alpelisib plus fulvestrant prolonged progression-free survival (PFS) compared to fulvestrant and placebo in men and postmenopausal women with hormone receptor positive (HR+), human epidermal growth factor receptor-2 (HER2)-negative advanced breast cancer, who rece...

What is the current status of trial NCT02437318?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 572 participants. The study started on 2015-07-23. Estimated completion is 2023-06-09.

What interventions are being tested in trial NCT02437318?

The interventions under investigation include: Placebo (DRUG), Fulvestrant (DRUG), Alpelisib (DRUG).

Who is sponsoring clinical trial NCT02437318?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.