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NCT02433379 · ClinicalTrials.gov registry record · NA

Understanding Outcomes With the EMBLEM™ S-ICD in Primary Prevention Patients With Low Ejection Fraction

A NA study of Ventricular Tachycardia and Ventricular Fibrillation, sponsored by Boston Scientific Corporation.

Completed
Registry status
NA
Development phase
1,173
Enrollment target
20
Study locations

NCT02433379 is a NA study of Ventricular Tachycardia and Ventricular Fibrillation that has completed, run by Boston Scientific Corporation. The registered enrollment target is 1,173 participants, above the 247-participant average among 28 other Ventricular Tachycardia trials with a reported enrollment target (375% higher). The trial reports 20 study locations across 8 states.

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The verdict

NCT02433379, a NA study of Ventricular Tachycardia and Ventricular Fibrillation, has completed, sponsored by Boston Scientific Corporation.

COMPLETED
Registry status
NA
Development phase
1,173 participants
Enrollment target
20
Study locations

Study Summary

This study assesses the 18-month incidence of inappropriate shocks in subjects implanted with the EMBLEM Subcutaneous Implantable Defibrillator (S-ICD) for primary prevention of sudden cardiac death. Devices are to be programmed with zone cutoffs at 200 bpm and 250 bmp in order to mimic the programming settings for transvenous ICDs in the MADIT RIT study. The incidence of inappropriate S-ICD shocks will be compared to the incidence of inappropriate shocks observed in the MADIT RIT study.

Interventions

  • DEVICE EMBLEM S-ICD System

Study Locations (20)

California

  • Glendale Adventist Medical Center - Glendale
  • Sharp Grossmont Hospital - La Mesa
  • University of Southern California Hospital - Los Angeles
  • Alta Bates Medical Center - Oakland
  • St. Joseph Hospital - Orange
  • Good Samaritan Hospital - San Jose - San Jose
  • Harbor UCLA Medical Center - Torrance

Florida

  • Baptist Medical Center - Jacksonville
  • Florida Hospital - Orlando
  • Tallahassee Memorial Hospital - Tallahassee

Alabama

  • Alabama Cardiovascular Group - Birmingham
  • Huntsville Hospital - The Heart Center, PC - Huntsville

Arizona

  • Mercy Gilbert Medical Center - Gilbert
  • Mayo Clinic Phoenix - Phoenix

Georgia

  • Emory University Hospital - Atlanta
  • University Hospital - Augusta

Illinois

  • CorVita Science Foundation - Chicago
  • Northwestern Memorial Hospital - Chicago

Connecticut

  • Yale University School of Medicine - New Haven

Delaware

  • Cardiology Physicians PA - Newark

Trial Details

FieldValue
Enrollment Target 1,173 participants
Start Date 2015-06-09
Est. Completion 2019-12-06
Phase NA

Sponsor

Boston Scientific Corporation

280 total trials

What the Registry Record Tells You About NCT02433379

The ClinicalTrials.gov registry entry for NCT02433379 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 1,173 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 247-participant average among 28 other Ventricular Tachycardia trials with a reported enrollment target (375% higher). The listed sponsor is Boston Scientific Corporation, which has 280 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Ventricular Tachycardia appearing as the primary indexed condition, and to 1 intervention - of which EMBLEM S-ICD System is the first listed.

NCT02433379 reports 20 study locations spanning 8 distinct geographic areas - top geographies include California, Florida, Alabama.

Frequently Asked Questions

What is clinical trial NCT02433379 about?

NCT02433379 is a clinical study titled "Understanding Outcomes With the EMBLEM™ S-ICD in Primary Prevention Patients With Low Ejection Fraction". This study assesses the 18-month incidence of inappropriate shocks in subjects implanted with the EMBLEM Subcutaneous Implantable Defibrillator (S-ICD) for primary prevention of sudden cardiac death. Devices are to be programmed with zone cutoffs at 200 bpm and 250 bmp in order to mimic the programm...

What is the current status of trial NCT02433379?

This trial is currently completed. It is a NA study. The enrollment target is 1,173 participants. The study started on 2015-06-09. Estimated completion is 2019-12-06.

What conditions does trial NCT02433379 study?

This clinical trial studies the following conditions: Ventricular Tachycardia, Ventricular Fibrillation, Low Cardiac Output.

What interventions are being tested in trial NCT02433379?

The interventions under investigation include: EMBLEM S-ICD System (DEVICE).

Who is sponsoring clinical trial NCT02433379?

This trial is sponsored by Boston Scientific Corporation, which has 280 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02433379 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Connecticut, Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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