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NCT02423070 · ClinicalTrials.gov registry record
Genome Transplant Dynamics
A clinical trial of Thoracic Organ Transplantation, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Recruiting
- Registry status
- 991
- Enrollment target
- 6
- Study locations
NCT02423070 is a study of Thoracic Organ Transplantation that is actively recruiting participants, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 991 participants. The trial reports 6 study locations across 3 states.
The verdict
NCT02423070, a study of Thoracic Organ Transplantation, is actively recruiting participants, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- RECRUITING
- Registry status
- 991 participants
- Enrollment target
- 6
- Study locations
Study Summary
Study Description: Heart and lung transplants can save lives, but long-term success is often limited by organ rejection that is hard to detect early. This study is testing a new, non-invasive blood test that looks for small pieces of DNA from the donor organ in the patient s blood. We believe higher levels of this donor DNA may signal early rejection before damage becomes permanent. Hypothesis: We believe that measuring donor-derived DNA in the blood can help detect early signs of rejection and improve outcomes for transplant patients. The study also collects genetic and biological samples to explore why some people are more at risk of complications after transplant. This may help guide future research and treatments. Who Can Join the Study: People receiving a heart or lung transplant (or both), age 14 and older People who are within three months of their transplant People who can understand and agree to take part in the study Participants will be asked to provide blood and other samples, and some of these will be used in lab research to explore new ideas about how and why transplant rejection happens. This research could lead to better ways to monitor and treat patients after a heart or lung transplant - and help improve long-term survival and quality of life.
Conditions Studied
Study Locations (6)
Maryland
- Johns Hopkins University - Baltimore
- University of Maryland - Baltimore
- National Institutes of Health Clinical Center - Bethesda
Virginia
- INOVA Fairfax Medical - Falls Church
- Virginia Commonwealth University - Richmond
District of Columbia
- MedStar Washington Hospital Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 991 participants |
| Start Date | 2015-06-25 |
| Est. Completion | 2034-11-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02423070
The ClinicalTrials.gov registry entry for NCT02423070 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 991 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Heart, Lung, and Blood Institute (NHLBI), which has 501 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Thoracic Organ Transplantation appearing as the primary indexed condition, and to 0 interventions.
NCT02423070 reports 6 study locations spanning 3 distinct geographic areas - top geographies include Maryland, Virginia, District of Columbia.
Frequently Asked Questions
What is clinical trial NCT02423070 about?
NCT02423070 is a clinical study titled "Genome Transplant Dynamics". Study Description: Heart and lung transplants can save lives, but long-term success is often limited by organ rejection that is hard to detect early. This study is testing a new, non-invasive blood test that looks for small pieces of DNA from the donor organ in the patient s blood. We believe highe...
What is the current status of trial NCT02423070?
This trial is currently recruiting. The enrollment target is 991 participants. The study started on 2015-06-25. Estimated completion is 2034-11-30.
What conditions does trial NCT02423070 study?
This clinical trial studies the following conditions: Thoracic Organ Transplantation.
Who is sponsoring clinical trial NCT02423070?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02423070 being conducted?
This trial has 6 study locations across District of Columbia, Maryland, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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