Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02421523 · ClinicalTrials.gov registry record · NA
Strength Training in Duchenne Muscular Dystrophy
A NA study, sponsored by University of Florida.
- Completed
- Registry status
- NA
- Development phase
- 18
- Enrollment target
NCT02421523 is a NA study that has completed, run by University of Florida. The registered enrollment target is 18 participants.
The verdict
NCT02421523, a NA study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 18 participants
- Enrollment target
Study Summary
Duchenne muscular dystrophy (DMD) is a debilitating neuromuscular disease that causes muscle breakdown, weakness, and eventual death. Over the last 40 years parents have received little guidance on the potential of exercise as a therapeutic strategy to maintain muscle function. It is well known that high intensity exercise and eccentric contractions can result in muscle damage in dystrophic muscle, yet the absence of muscle loading will conversely result in muscle wasting. Recent research in rodent models and milder forms of muscular dystrophy supports earlier studies that resistance exercise may have beneficial effects for maintenance of muscle mass in dystrophic muscle. However, careful and systematic investigation into the safety and feasibility of resistance exercise is needed to consider its implementation in boys with DMD. The goal of this project is to assess the safety and feasibility of a home based mild to moderate-intensity strengthening exercise program in boys with Duchenne muscular dystrophy (DMD). Evidence from milder forms of muscular dystrophy and mouse models of DMD suggests that strengthening exercise may be beneficial for these children, but this area has not been adequately explored using human subjects. The results of this study should provide information to assist in the development of scientifically based recommendations concerning optimal exercise parameters for patients with DMD.
Interventions
- PROCEDURE Aim 2 Exercise group
- PROCEDURE Aim 1 Exercise Dosing
- PROCEDURE Aim 2 Control group
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2015-05-30 |
| Est. Completion | 2018-10-08 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02421523
The ClinicalTrials.gov registry entry for NCT02421523 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Aim 2 Exercise group is the first listed.
NCT02421523 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02421523 about?
NCT02421523 is a clinical study titled "Strength Training in Duchenne Muscular Dystrophy". Duchenne muscular dystrophy (DMD) is a debilitating neuromuscular disease that causes muscle breakdown, weakness, and eventual death. Over the last 40 years parents have received little guidance on the potential of exercise as a therapeutic strategy to maintain muscle function. It is well known that...
What is the current status of trial NCT02421523?
This trial is currently completed. It is a NA study. The enrollment target is 18 participants. The study started on 2015-05-30. Estimated completion is 2018-10-08.
What interventions are being tested in trial NCT02421523?
The interventions under investigation include: Aim 2 Exercise group (PROCEDURE), Aim 1 Exercise Dosing (PROCEDURE), Aim 2 Control group (PROCEDURE).
Who is sponsoring clinical trial NCT02421523?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.