Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02412878 · ClinicalTrials.gov registry record · Phase 3

Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma

A Phase 3 study, sponsored by Amgen.

Completed
Registry status
Phase 3
Development phase
478
Enrollment target

NCT02412878 is a Phase 3 study that has completed, run by Amgen. The registered enrollment target is 478 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02412878, a Phase 3 study, has completed, sponsored by Amgen.

COMPLETED
Registry status
Phase 3
Development phase
478 participants
Enrollment target

Study Summary

The purpose of the study is to compare the progression-free survival (PFS) of once-weekly carfilzomib dosing in combination with dexamethasone to twice-weekly carfilzomib dosing in combination with dexamethasone in adults with relapsed and refractory multiple myeloma, previously treated with bortezomib and an immunomodulatory agent (IMiD).

Interventions

  • DRUG Dexamethasone
  • DRUG Carfilzomib

Trial Details

FieldValue
Enrollment Target 478 participants
Start Date 2015-09-09
Est. Completion 2019-01-07
Phase Phase 3

Sponsor

Amgen

558 total trials

What the Registry Record Tells You About NCT02412878

The ClinicalTrials.gov registry entry for NCT02412878 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 478 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Dexamethasone is the first listed.

NCT02412878 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02412878 about?

NCT02412878 is a clinical study titled "Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma". The purpose of the study is to compare the progression-free survival (PFS) of once-weekly carfilzomib dosing in combination with dexamethasone to twice-weekly carfilzomib dosing in combination with dexamethasone in adults with relapsed and refractory multiple myeloma, previously treated with bortezo...

What is the current status of trial NCT02412878?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 478 participants. The study started on 2015-09-09. Estimated completion is 2019-01-07.

What interventions are being tested in trial NCT02412878?

The interventions under investigation include: Dexamethasone (DRUG), Carfilzomib (DRUG).

Who is sponsoring clinical trial NCT02412878?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.