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NCT02405442 · ClinicalTrials.gov registry record · Phase 2

Safety and Efficacy of Andecaliximab in Participants With Moderately to Severely Active Crohn's Disease

A Phase 2 study, sponsored by Gilead Sciences.

Terminated
Registry status
Phase 2
Development phase
187
Enrollment target

NCT02405442 is a Phase 2 study that was terminated before completion, run by Gilead Sciences. The registered enrollment target is 187 participants.

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The verdict

NCT02405442, a Phase 2 study, was terminated before completion, sponsored by Gilead Sciences.

TERMINATED
Registry status
Phase 2
Development phase
187 participants
Enrollment target

Study Summary

This study will primarily evaluate the safety and efficacy of andecaliximab in adults with active Crohn's disease. The study will consist of a Double-Blind Phase of 8 weeks followed by an Open-Label Extension. Participants who complete the Double-Blind Phase will be eligible to enroll in the optional Open-Label Extension for an additional 44 weeks. Participants who complete Week 52 assessments will be eligible to enter the Extended Treatment Phase to continue treatment with andecaliximab for an additional 156 weeks.

Interventions

  • DRUG Placebo
  • DRUG Andecaliximab

Trial Details

FieldValue
Enrollment Target 187 participants
Start Date 2015-04-30
Est. Completion 2016-12-22
Phase Phase 2

Sponsor

Gilead Sciences

504 total trials

What the Registry Record Tells You About NCT02405442

The ClinicalTrials.gov registry entry for NCT02405442 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 187 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 504 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02405442 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02405442 about?

NCT02405442 is a clinical study titled "Safety and Efficacy of Andecaliximab in Participants With Moderately to Severely Active Crohn's Disease". This study will primarily evaluate the safety and efficacy of andecaliximab in adults with active Crohn's disease. The study will consist of a Double-Blind Phase of 8 weeks followed by an Open-Label Extension. Participants who complete the Double-Blind Phase will be eligible to enroll in the optiona...

What is the current status of trial NCT02405442?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 187 participants. The study started on 2015-04-30. Estimated completion is 2016-12-22.

What interventions are being tested in trial NCT02405442?

The interventions under investigation include: Placebo (DRUG), Andecaliximab (DRUG).

Who is sponsoring clinical trial NCT02405442?

This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.