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RECRUITING Phase 1

A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myeloma

NCT06153251 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess BMS-986453 in participants with relapsed and/or refractory multiple myeloma (RRMM).

Interventions

  • DRUG Cyclophosphamide
  • DRUG Fludarabine
  • DRUG BMS-986453

Study Locations (19)

Other

  • Hôpital Saint-Louis — Paris
  • Universitaetsklinikum Koeln — Cologne
  • Universitaetsklinikum Heidelberg — Heidelberg
  • Universitaetsklinikum Wuerzburg — Würzburg
  • Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca — Salamanca

California

  • City of Hope Comprehensive Cancer Center — Duarte
  • UCSF Helen Diller Medical Center at Parnassus Heights — San Francisco
  • Stanford University Medical Center — Stanford

New York

  • Icahn School of Medicine at Mount Sinai — New York
  • Memorial Sloan Kettering Cancer Center — New York

Tennessee

  • Local Institution - 0008 — Nashville
  • Tennessee Oncology — Nashville

Alabama

  • University of Alabama at Birmingham — Birmingham

Colorado

  • Colorado Blood Cancer Institute — Denver

Connecticut

  • Yale Cancer Center — New Haven

Florida

  • Moffitt Cancer Center — Tampa

Trial Details

FieldValue
Enrollment Target 187 participants
Start Date 2024-01-23
Est. Completion 2030-05-02
Phase Phase 1

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06153251

The ClinicalTrials.gov registry entry for NCT06153251 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 187 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Juno Therapeutics, Inc., a Bristol-Myers Squibb Company, which has 12 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Relapsed and/or Refractory Multiple Myeloma appearing as the primary indexed condition, and to 3 interventions — of which Cyclophosphamide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06153251 reports 19 study locations spanning 11 distinct geographic areas — top geographies include Other, California, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06153251 about?

NCT06153251 is a clinical study titled "A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myeloma". The purpose of this study is to assess BMS-986453 in participants with relapsed and/or refractory multiple myeloma (RRMM).

What is the current status of trial NCT06153251?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 187 participants. The study started on 2024-01-23. Estimated completion is 2030-05-02.

What conditions does trial NCT06153251 study?

This clinical trial studies the following conditions: Relapsed and/or Refractory Multiple Myeloma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06153251?

The interventions under investigation include: Cyclophosphamide (DRUG), Fludarabine (DRUG), BMS-986453 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06153251?

This trial is sponsored by Juno Therapeutics, Inc., a Bristol-Myers Squibb Company, which has 12 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06153251 being conducted?

This trial has 19 study locations across Alabama, California, Colorado, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial