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NCT02365662 · ClinicalTrials.gov registry record · Phase 1
A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor
A Phase 1 study, sponsored by AbbVie.
- Terminated
- Registry status
- Phase 1
- Development phase
- 46
- Enrollment target
NCT02365662: Clinical Trial Phase 1 study, sponsored by AbbVie.
NCT02365662 is a Phase 1 study that was terminated before completion, run by AbbVie. The registered enrollment target is 46 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (23% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02365662, a Phase 1 study, was terminated before completion, sponsored by AbbVie.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 46 participants
- Enrollment target
Study Summary
This is an open-label, Phase I, dose escalation study to determine the recommended Phase 2 dose, maximum tolerated dose, and evaluate the safety and pharmacokinetic profile of ABBV-221 in participants with advanced solid tumors likely to exhibit elevated levels of Epidermal Growth Factor Receptor (EGFR).
Primary Outcome
Adverse event monitoring will be performed during the study
Interventions
- DRUG ABBV-221
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2015-01-09 |
| Est. Completion | 2018-03-15 |
| Phase | Phase 1 |
Why NCT02365662 stopped before completion
NCT02365662 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (23% lower).
The record links to 0 conditions, and to 1 intervention - of which ABBV-221 is the first listed.
NCT02365662 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02365662 about?
NCT02365662 is a clinical study titled "A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor". This is an open-label, Phase I, dose escalation study to determine the recommended Phase 2 dose, maximum tolerated dose, and evaluate the safety and pharmacokinetic profile of ABBV-221 in participants with advanced solid tumors likely to exhibit elevated levels of Epidermal Growth Factor Receptor (E...
What is the current status of trial NCT02365662?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 46 participants. The study started on 2015-01-09. Estimated completion is 2018-03-15.
What interventions are being tested in trial NCT02365662?
The interventions under investigation include: ABBV-221 (DRUG).
Who is sponsoring clinical trial NCT02365662?
This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02365662's enrollment target sits among peer trials
46 1058th of 2000 higher than 935 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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