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NCT02361944 · ClinicalTrials.gov registry record · Phase 2
Risk of Oxygen During Cardiac Surgery Trial
A Phase 2 study, sponsored by Vanderbilt University.
- Completed
- Registry status
- Phase 2
- Development phase
- 213
- Enrollment target
NCT02361944: Completed Phase 2 study, sponsored by Vanderbilt University.
NCT02361944 is a Phase 2 study that has completed, run by Vanderbilt University. The registered enrollment target is 213 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (60% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02361944, a Phase 2 study, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 213 participants
- Enrollment target
Study Summary
The investigators will recruit and randomize 200 elective cardiac surgery patients to receive physiologic oxygenation (normoxia) or hyper-oxygenation (hyperoxia) during surgery to test the hypothesis that intraoperative physiologic oxygenation decreases the generation of reactive oxygen species, oxidative damage, and postoperative organ injury compared to hyper-oxygenation.
Primary Outcome
quantified by measuring F2-isoprostanes isofurans following separation from cardiopulmonary bypass or completion of off-pump coronary artery bypass grafting
Interventions
- DRUG Oxygen - normoxia
- DRUG Oxygen - hyperoxia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 213 participants |
| Start Date | 2016-04-05 |
| Est. Completion | 2021-01-08 |
| Phase | Phase 2 |
What the finished NCT02361944 record still lists
NCT02361944 is an interventional study that assigns participants to a tested intervention. The registered 213 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (60% higher).
The record links to 0 conditions, and to 2 interventions - of which Oxygen - normoxia is the first listed.
NCT02361944 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02361944 about?
NCT02361944 is a clinical study titled "Risk of Oxygen During Cardiac Surgery Trial". The investigators will recruit and randomize 200 elective cardiac surgery patients to receive physiologic oxygenation (normoxia) or hyper-oxygenation (hyperoxia) during surgery to test the hypothesis that intraoperative physiologic oxygenation decreases the generation of reactive oxygen species, oxi...
What is the current status of trial NCT02361944?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 213 participants. The study started on 2016-04-05. Estimated completion is 2021-01-08.
What interventions are being tested in trial NCT02361944?
The interventions under investigation include: Oxygen - normoxia (DRUG), Oxygen - hyperoxia (DRUG).
Who is sponsoring clinical trial NCT02361944?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02361944's enrollment target sits among peer trials
213 290th of 2000 higher than 1,711 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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