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COMPLETED Phase 1

Combination Therapy With Carfilzomib, Romidepsin, Lenalidomide in Patients With Relapsed or Refractory B- and T-cell Lymphomas

NCT02341014 · View on ClinicalTrials.gov ↗

Study Summary

This is an open label phase Ib/IIa study of patients with relapsed/refractory B- and T-cell lymphomas who are treated with carfilzomib, lenalidomide and romidepsin.

Interventions

  • DRUG Lenalidomide
  • DRUG Carfilzomib
  • DRUG Romidepsin

Study Locations (6)

New York

  • Memorial Sloan Kettering Cancer Center @ Suffolk — Commack
  • Memorial Sloan Kettering Westchester — Harrison
  • Memorial Sloan Kettering Cancer Center — New York
  • Memorial Sloan Kettering at Mercy Medical Center — Rockville Centre

Nebraska

  • University of Nebraska Medical Center — Omaha

New Jersey

  • Memoral Sloan Kettering Cancer Center — Basking Ridge

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2015-01-02
Est. Completion 2023-01-11
Phase Phase 1

Sponsor

Memorial Sloan Kettering Cancer Center

2,280 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02341014

The ClinicalTrials.gov registry entry for NCT02341014 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 2,280 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with T-cell Lymphomas appearing as the primary indexed condition, and to 3 interventions — of which Lenalidomide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02341014 reports 6 study locations spanning 3 distinct geographic areas — top geographies include New York, Nebraska, New Jersey. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02341014 about?

NCT02341014 is a clinical study titled "Combination Therapy With Carfilzomib, Romidepsin, Lenalidomide in Patients With Relapsed or Refractory B- and T-cell Lymphomas". This is an open label phase Ib/IIa study of patients with relapsed/refractory B- and T-cell lymphomas who are treated with carfilzomib, lenalidomide and romidepsin.

What is the current status of trial NCT02341014?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2015-01-02. Estimated completion is 2023-01-11.

What conditions does trial NCT02341014 study?

This clinical trial studies the following conditions: T-cell Lymphomas, Relapsed or Refractory. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02341014?

The interventions under investigation include: Lenalidomide (DRUG), Carfilzomib (DRUG), Romidepsin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02341014?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 2,280 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02341014 being conducted?

This trial has 6 study locations across Nebraska, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial