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NCT02318277 · ClinicalTrials.gov registry record · Phase 1
A Study of Epacadostat (INCB024360) in Combination With Durvalumab (MEDI4736) in Subjects With Selected Advanced Solid Tumors (ECHO-203)
A Phase 1 study, sponsored by Incyte Corporation.
- Completed
- Registry status
- Phase 1
- Development phase
- 176
- Enrollment target
NCT02318277: Completed Phase 1 study, sponsored by Incyte Corporation.
NCT02318277 is a Phase 1 study that has completed, run by Incyte Corporation. The registered enrollment target is 176 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (193% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02318277, a Phase 1 study, has completed, sponsored by Incyte Corporation.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 176 participants
- Enrollment target
Study Summary
The purpose of this study is to explore the safety, tolerability, pharmacokinetics, immunogenicity and preliminary efficacy of INCB024360 administered in combination with MEDI4736 in subjects with selected advanced solid tumors.
Primary Outcome
Adverse events reported for the first time or worsening of a pre-existing event after first dose of study drug/treatment
Interventions
- DRUG MEDI4736
- DRUG INCB024360
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 176 participants |
| Start Date | 2015-01-05 |
| Est. Completion | 2020-10-16 |
| Phase | Phase 1 |
What the finished NCT02318277 record still lists
NCT02318277 is an interventional study that assigns participants to a tested intervention. The registered 176 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (193% higher).
The record links to 0 conditions, and to 2 interventions - of which MEDI4736 is the first listed.
NCT02318277 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02318277 about?
NCT02318277 is a clinical study titled "A Study of Epacadostat (INCB024360) in Combination With Durvalumab (MEDI4736) in Subjects With Selected Advanced Solid Tumors (ECHO-203)". The purpose of this study is to explore the safety, tolerability, pharmacokinetics, immunogenicity and preliminary efficacy of INCB024360 administered in combination with MEDI4736 in subjects with selected advanced solid tumors.
What is the current status of trial NCT02318277?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 176 participants. The study started on 2015-01-05. Estimated completion is 2020-10-16.
What interventions are being tested in trial NCT02318277?
The interventions under investigation include: MEDI4736 (DRUG), INCB024360 (DRUG).
Who is sponsoring clinical trial NCT02318277?
This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02318277's enrollment target sits among peer trials
176 316th of 2000 higher than 1,682 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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