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NCT02309580 · ClinicalTrials.gov registry record · Phase 1

Study of Ibrutinib in Relapsed and Refractory T-cell Lymphoma

A Phase 1 study, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 1
Development phase
14
Enrollment target

NCT02309580: Completed Phase 1 study, sponsored by Memorial Sloan Kettering Cancer Center.

NCT02309580 is a Phase 1 study that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 14 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT02309580, a Phase 1 study, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
14 participants
Enrollment target

Study Summary

This is a Phase 1 clinical trial, a type of research study. The purpose of this phase 1 clinical trial is to find out whether a new study drug, ibrutinib, is safe in patients with T-cell non-Hodgkin lymphoma that has either come back or not responded to treatment. In this phase 1 study, different doses of ibrutinib (560 mg and 840 mg daily) will be tested to see what effect the drug has on the patient and the disease.

Primary Outcome

evaluate the safety and toxicities of ibrutinib in patients with relapsed/refractory Tcell lymphoma (PTCL and CTCL) as defined by CTCAE version 4.

Interventions

  • DRUG Ibrutinib

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2015-01
Est. Completion 2023-05-08
Phase Phase 1
Memorial Sloan Kettering Cancer Center

1,884 total trials

What the finished NCT02309580 record still lists

NCT02309580 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 1 intervention - of which Ibrutinib is the first listed.

NCT02309580 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02309580 about?

NCT02309580 is a clinical study titled "Study of Ibrutinib in Relapsed and Refractory T-cell Lymphoma". This is a Phase 1 clinical trial, a type of research study. The purpose of this phase 1 clinical trial is to find out whether a new study drug, ibrutinib, is safe in patients with T-cell non-Hodgkin lymphoma that has either come back or not responded to treatment. In this phase 1 study, different do...

What is the current status of trial NCT02309580?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2015-01. Estimated completion is 2023-05-08.

What interventions are being tested in trial NCT02309580?

The interventions under investigation include: Ibrutinib (DRUG).

Who is sponsoring clinical trial NCT02309580?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02309580's enrollment target sits among peer trials

14 1844th of 2000 higher than 154 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02309580, the US trial registry maintained by the National Library of Medicine. NCT02309580 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.