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NCT02279641 · ClinicalTrials.gov registry record · Phase 1

RDEA3170 and Allopurinol Combination Study in Gout Subjects

A Phase 1 study, sponsored by Ardea Biosciences.

Completed
Registry status
Phase 1
Development phase
12
Enrollment target

NCT02279641: Completed Phase 1 study, sponsored by Ardea Biosciences.

NCT02279641 is a Phase 1 study that has completed, run by Ardea Biosciences. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02279641, a Phase 1 study, has completed, sponsored by Ardea Biosciences.

COMPLETED
Registry status
Phase 1
Development phase
12 participants
Enrollment target

Study Summary

This is a Phase 1b, randomized, open-label, drug-drug interaction study in adult male subjects with gout. It is designed to assess the pharmacokinetics (PK) and pharmacodynamics (PD) of RDEA3170 or allopurinol alone and in combination in the fed state.

Primary Outcome

Cmax of Allopurinol/Oxypurinol Alone and In Combination with RDEA3170

Interventions

  • DRUG allopurinol 300 mg
  • DRUG RDEA3170 10 mg

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2014-11-01
Est. Completion 2015-09-11
Phase Phase 1
Ardea Biosciences

32 total trials

What the finished NCT02279641 record still lists

NCT02279641 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).

The record links to 0 conditions, and to 2 interventions - of which allopurinol 300 mg is the first listed.

NCT02279641 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02279641 about?

NCT02279641 is a clinical study titled "RDEA3170 and Allopurinol Combination Study in Gout Subjects". This is a Phase 1b, randomized, open-label, drug-drug interaction study in adult male subjects with gout. It is designed to assess the pharmacokinetics (PK) and pharmacodynamics (PD) of RDEA3170 or allopurinol alone and in combination in the fed state.

What is the current status of trial NCT02279641?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2014-11-01. Estimated completion is 2015-09-11.

What interventions are being tested in trial NCT02279641?

The interventions under investigation include: allopurinol 300 mg (DRUG), RDEA3170 10 mg (DRUG).

Who is sponsoring clinical trial NCT02279641?

This trial is sponsored by Ardea Biosciences, which has 32 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02279641's enrollment target sits among peer trials

12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02279641, the US trial registry maintained by the National Library of Medicine. NCT02279641 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.