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NCT02272270 · ClinicalTrials.gov registry record · Phase 1

Phase I Newly Diagnosed GBM With Temozolomide, Radiation, and Minocycline Followed by Adjuvant Minocycline/Temozolomide (D-TERMINED)

A Phase 1 study, sponsored by University of Utah.

Completed
Registry status
Phase 1
Development phase
25
Enrollment target

NCT02272270 is a Phase 1 study that has completed, run by University of Utah. The registered enrollment target is 25 participants.

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The verdict

NCT02272270, a Phase 1 study, has completed, sponsored by University of Utah.

COMPLETED
Registry status
Phase 1
Development phase
25 participants
Enrollment target

Study Summary

This will be an open label, single arm study. Subjects with newly diagnosed high grade glioma will begin minocycline one week prior to beginning postoperative chemoradiation and continue it until progression, intolerance, or the end of adjuvant temozolomide, whichever comes first.

Interventions

  • DRUG Minocycline with chemoradiation (temozolomide and radiation therapy)

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2014-10-27
Est. Completion 2018-02-18
Phase Phase 1

Sponsor

University of Utah

818 total trials

What the Registry Record Tells You About NCT02272270

The ClinicalTrials.gov registry entry for NCT02272270 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Minocycline with chemoradiation (temozolomide and radiation therapy) is the first listed.

NCT02272270 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02272270 about?

NCT02272270 is a clinical study titled "Phase I Newly Diagnosed GBM With Temozolomide, Radiation, and Minocycline Followed by Adjuvant Minocycline/Temozolomide (D-TERMINED)". This will be an open label, single arm study. Subjects with newly diagnosed high grade glioma will begin minocycline one week prior to beginning postoperative chemoradiation and continue it until progression, intolerance, or the end of adjuvant temozolomide, whichever comes first.

What is the current status of trial NCT02272270?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2014-10-27. Estimated completion is 2018-02-18.

What interventions are being tested in trial NCT02272270?

The interventions under investigation include: Minocycline with chemoradiation (temozolomide and radiation therapy) (DRUG).

Who is sponsoring clinical trial NCT02272270?

This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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